›› 2012, Vol. 27 ›› Issue (2): 88-90.

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The correlation analysis the thromboelastogram and conventional coagulation tests in patients with acute cerebral infarction

  

  1. 1. Department of Transfusion,Zhejiang Province People′s Hospital, Zhejiang Hangzhou 310014,China; 2.Department of Clinical Laboratory,Zhejiang Traditional Chinese Medical Hospital,Zhejiang Hangzhou 310006,China
  • Online:2012-02-28 Published:2012-02-19

Abstract: Objective To investigate the correlations between the thromboelastogram (TEG) and conventional coagulation tests in patients with acute cerebral infarction, and evaluate the 2 methods′ commonness and differences in determining the blood coagulation of acute cerebral infarction. Methods A total of 107 patients with acute cerebral infarction were enrolled,and all patients were determined by TEG and conventional coagulation tests simultaneously. Results The reaction time (R) and prothrombin formation time (K) in the dead patients with acute cerebral infarction were significantly shorter than those in the controls,and the results of prothrombin time (PT) and activated partial thromboplastin time (APTT) were low. There were correlations between the TEG and conventional coagulation tests. The R and K times of TEG parameters were positively correlated with the prothrombin timeinternational normalized ratio (PTINR), and were negatively correlated with fibrinogen (FIB). α angle and maximal amplitude (MA) were negatively correlated with the PTINR,and were positively correlated with FIB. Conclusions TEG parameters not only can reflect more fully in the body′s blood clotting process, but also have correlations with conventional coagulation tests in patients with acute cerebral infarction. TEG and conventional coagulation tests can be conducted simultaneously and have mutual complementary effect.

Key words: Thromboelastogram, Coagulation test, Cerebral infarction