Abstract: To analyze the drug resistance characteristics and in vitro adhesion abilities of Acinetobacter baumannii with different genotypes, to provide the reference for further study on the relationship between the evolution of drug resistance of Acinetobacter baumannii and its adhesion ability change, and to guide infection prevention and control. Pulsed field gel electrophoresis(PFGE) was used to do molecular typing for 50 isolates of Acinetobacter baumannii from different inpatients in Inner Mongolia. In vitro adhesion abilities of Acinetobacter baumannii with different genotypes were detected by fibronectin adherence assay. The 50 isolates had 22 PFGE genotypes, among which A and E types were the advantageous types, and the rates were 22%(11/50)and 24%(12/50), while the isolates with L type were resistant to all tested antibiotics, and the drug resistance of the isolates belonging to the remaining genotypes were significantly different. The isolates of A type were mainly isolated from 2 regions, Xing'an Meng and Chifeng City. The isolates of E type were all isolated from Hohhot. Fibronectin adherence assay showed that the isolates with G type and J type showed the highest in vitro adhesion ability, while the isolates with J type were sensitive to all tested antibiotics, and the isolates with D type showed the lowest in vitro adhesion ability, only being resistant to carbapenem. The genotypes of Acinetobacter baumannii isolated from Inner Mongolia show diverse features, which seems to be specific with different districts. There is no significant correlation between the drug resistance acceleration of Acinetobacter baumannii and its in vitro adhesion abilities.

Key words: Acinetobacter baumannii, Drug resistance, Pulsed field gel electrophoresis, Molecular typing, In vitro adhesion ability