Research progress on drug resistance and treatment strategies of hypervirulent Klebsiella pneumoniae

doi:10.3969/j.issn.1673-8640.2023.01.018

Abstract

Abstract:

In the past 30 years，hypervirulent Klebsiella pneumoniae（hvKP） isolates have been increasing. Once it was believed that the hypervirulence and high drug resistance would not occur in the same Klebsiella pneumoniae（KP） isolate. However，the recent reports on drug resistance and multi-drug resistance of hvKP isolates have emerged one after another. Therefore，the hypervirulence of hvKP and its combination with multi-drug resistance is likely to become an important clinical challenge. This review focuses on the epidemiology，determination methods，drug resistance and treatment of hvKP，in order to provide a reference for the clinical determination，treatment，prevention and control of multi-drug resistant hvKP.

Key words: Klebsiella pneumoniae, Virulence, Drug resistance, Treatment

CLC Number:

R378.2

WANG Su, DING Li, JIANG Wenrong, MIAO Yingxin, ZHANG Yanmei, ZHAO Hu. Research progress on drug resistance and treatment strategies of hypervirulent Klebsiella pneumoniae[J]. Laboratory Medicine, 2023, 38(1): 81-86.

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