Abstract: Objective To analyze bacterial distribution and drug resistance of urinary tract infection, and to provide the reference for clinical rational use of antimicrobial agents. Methods A retrospective investigation was performed. The isolates from urine specimens were analyzed. Results There were 962 isolates including 701 isolates of gram negative bacilli (72.9%) and 261 isolates of gram positive cocci (27.1%). There were Escherichia coli (429 isolates, 44.6%), following 228 isolates of Enterococcus (23.7%) and 83 isolates of Klebsiella pneumoniae (8.6%). The drug resistance rates of Escherichia coli and Klebsiella pneumoniae to quinolone were 77.9% and 47.0%. The drug resistance rates to cefotaxime were 62.9%and 57.8%. The drug resistance rate of Enterococcus faecium was higher than that of Enterococcus faecalis, and there was no isolate resistant to vancomycin. Conclusions The main pathogenic bacteria of urinary culture are Escherichia coli as the representative of gram negative bacilli. The drug resistances to quinolone and the 3rd and 4th generation cephalosporins are serious.

Key words: Urinary culture, Bacterial distribution, Drug resistance