检验医学 ›› 2014, Vol. 29 ›› Issue (11): 1141-1143.DOI: 10.3969/j.issn.1673-8640.2014.11.015

• 临床应用研究·论著 • 上一篇    下一篇

63株嗜麦芽寡养单胞菌的临床分布与耐药性分析

徐飞,刘雪梅,迟富丽,谈华,常勇,曹波   

  1. 南京医科大学附属南京儿童医院检验科,江苏 南京 210008
  • 收稿日期:2014-07-15 出版日期:2014-11-01 发布日期:2014-11-28
  • 作者简介:徐飞,男,1975年生,硕士,副主任技师,主要从事临床微生物检验工作。

Clinical distribution and drug resistance analysis for 63 isolates of Stenotrophomonas maltophilia

XU Fei, LIU Xuemei, CHI Fuli, TAN Hua, CHANG Yong, CAO Bo   

  1. Department of Clinical Laboratory, the Children's Hospital Affiliated to Nanjing Medical University, Jiangsu Nanjing 210008, China
  • Received:2014-07-15 Online:2014-11-01 Published:2014-11-28

摘要:

目的 了解嗜麦芽寡养单胞菌的临床分布及对抗菌药物的耐药性。方法 采用VITEK-2 COMPACT全自动微生物鉴定仪及纸片扩散(K-B)法对分离的63株嗜麦芽寡养单胞菌的来源分布、药物敏感性结果进行统计分析。结果 63株嗜麦芽寡养单胞菌在临床标本中分布以痰液为主,占87.3%;感染主要发生在新生儿科为17.4%和胸外科17.4%;其次为呼吸科14.3%和重症监护病房(ICU)14.3%;嗜麦芽寡养单胞菌对亚胺培南耐药率为100.0%;而对左氧氟沙星、米诺环素、磺胺甲口恶唑-甲氧苄啶耐药率较低分别为1.6%、3.2%、3.2%。结论 应加强对嗜麦芽寡养单胞菌耐药性监测,以指导临床根据药物敏感性试验结果合理选择抗菌药物。

关键词: 嗜麦芽寡养单胞菌, 耐药性, 抗菌药物

Abstract:

Objective To investigate the clinical distribution and drug resistance of Stenotrophomonas maltophilia. Methods The clinical distribution and drug resistance analysis for 63 isolates of Stenotrophomonas maltophilia(K-B) method. The results were analyzed statistically. Results The isolation rate was the highest in respiratory specimens . There was a highest isolation rate of 87.3%. The samples were mainly obtained from the wards of Neonatology Department(17.4%) and Thoracic Surgery(17.4%), followed by Respiratory Department(4.3%) and Intensive Care Unit(ICU)(14.3%). The 63 isolates of Stenotrophomonas maltophilia, and the resistance rate was 100.0%. The resistance rates to levofloxacin, minocyline and triethoprim-sulfamethoxazole were 1.6%, 3.2% and 3.2%. Conclusions It should enhance drug resistance monitoring of Stenotrophomonas maltophilia. Treatment based on drug susceptibility test should be adapted as soon as possible. were highly resistant to imipenem were performed by VITEK-2 COMPACT system and Kirby-Bauer.

Key words: Stenotrophomonas maltophilia, Drug resistance, Antibiotic

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