关节置换术后假体周围感染的实验室诊断

doi:10.3969/j.issn.1673-8640.2020.01.016

摘要/Abstract

摘要：

关节假体周围感染（PJI）是关节置换术后发生的严重并发症,需尽快明确诊断、积极治疗,以避免产生严重的不良后果。由于实验室传统检查方法敏感性和特异性的限制,PJI的诊断至今仍面临巨大挑战。近年来,一些兼具高敏感性和高特异性的检测方法,包括生物标志物检测和病原学检测方法在PJI诊断方面具有良好的应用前景。文章对关节置换术后PJI早期诊断的研究进展作一综述,以便为临床诊治提供参考。

关键词: 假体周围感染, 实验诊断, 生物标志物, 微生物学技术

Abstract:

Periprosthetic joint infection（PJI） is a serious complication in total joint arthroplasty patients,which leads to severe consequences if unresolved timely. Because of the low sensitivity and specificity of the conventional diagnostic tools,the diagnosis of PJI is still a challenge in modern medicine. In the recent years,some new diagnostic techniques,with high sensitivity and specificity,such as biomarker determination and the culture of pathogenic bacteria,have been developed. This review is to provide a comprehensive and up-to-date review on the diagnostic strategies for PJI.

Key words: Periprosthetic joint infection, Laboratory diagnosis, Biomarker, Microbiological technique

中图分类号:

R446.1

潘允琪, 汤瑾, 王坚镪, 李运改. 关节置换术后假体周围感染的实验室诊断[J]. 检验医学, 2020, 35(1): 75-78.

PAN Yunqi, TANG Jin, WANG Jianqiang, LI Yungai. Laboratory diagnosis of periprosthetic joint infection after total joint arthroplasty[J]. Laboratory Medicine, 2020, 35(1): 75-78.

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