Research progress on the relationship between drug resistance and controlling biofilm formation by sRNA

doi:10.3969/j.issn.1673-8640.2017.06.023

Abstract

Abstract:

Small non-coding RNA （sRNA） is a gene expression regulatory factor that is discovered nearly. It is in non-encoding region of bacterial genome,which regulates the expression of target genes in the post-transcriptional level．It affects the physiological functions of cells,such as individual development,the activation of translation,inhibition of translation,bacterial toxicity and so on．In recent years,lots of studies confirm that sRNA has relations with the drug resistance of bacteria and the formation of bacterial biofilm．This review will give a brief overview about sRNA for the formation of bacterial biofilm and its effects on bacteria．

Key words: Small non-coding RNA, Drug resistance, Biofilm, Bacteria

CLC Number:

R446.5

MO Qianqian, MO Jiaguang. Research progress on the relationship between drug resistance and controlling biofilm formation by sRNA[J]. Laboratory Medicine, 2017, 32(6): 549-552.

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