Laboratory Medicine ›› 2021, Vol. 36 ›› Issue (11): 1135-1139.DOI: 10.3969/j.issn.1673-8640.2021.11.009

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Respiratory tract virus surveillance and analysis of pneumonia inpatients from 2017 to 2020 in Yangzhou

HUANG Yao1, ZHANG Xiuling1, WANG Yan1, KONG Guimei2, XU Qin1()   

  1. 1. Department of Clinical Laboratory,Yangzhou Center for Disease Control and Prevention,Yangzhou 225002,Jiangsu,China
    2. Medical School of Yangzhou University,Yangzhou 225009,Jiangsu,China
  • Received:2020-08-30 Online:2021-11-30 Published:2021-12-20
  • Contact: XU Qin

Abstract:

Objective To analyze the results of respiratory tract virus surveillance of pneumonia inpatients in Yangzhou,and to investigate the prevalence of respiratory tract viruses in Yangzhou. Methods From 2017 to 2020,the throat swab samples of pneumonia inpatients in Yangzhou were determined for 5 respiratory tract viruses by fluorescence quantitative polymerase chain reaction(PCR),and the results were analyzed. Results In the 1 479 throat swab samples,195(13.18%) positive cases were determined. There were 7 cases(0.47%) of mixed 2-virus infection. The top 3 viruses with high determination rates were influenza virus(5.54%),human respiratory syncytial virus(2.63%) and human enterovirus(1.89%). The peak of positive determination rate of respiratory tract virus in pneumonia inpatients was mainly concentrated in March-May and November-December in 2017,in July and September in 2018,in January-March and December in 2019 and in September in 2020. In the positive cases of respiratory tract virus,the determination rate of females was higher than that of males(χ2=6.26,P<0.05). Children of 0-6 years old had the highest positive determination rate(χ2=15.87,P<0.05). There was no statistical significance in the composition of respiratory pathogen spectrum between males and females(χ2=7.68,P>0.05). The composition of respiratory pathogen spectrum was different in different years and different ages (χ2 values were 6.26 and 27.33,P<0.01). Conclusions The epidemic season and respiratory pathogen spectrum in pneumonia inpatients in Yangzhou from 2017 to 2020 varied from year to year,but the main pathogens were influenza virus and respiratory syncytial virus. Children of 0-6 years old are the susceptible group,and females infected with respiratory tract virus are more likely to progress to pneumonia. Respiratory tract virus surveillance should be strengthened,and influenza virus and human respiratory syncytial virus should be taken as the focuses of the prevention and control of respiratory epidemic.

Key words: Respiratory tract virus, Prevalence characteristic, Inpatient, Pneumonia, Yangzhou

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