Abstract:

Objective To explore the early diagnosis significance and prognosis impact of D-dimer for acute aortic dissection (AAD). Methods 60 cases from October 2011 to February 2014 in the department of cardiovascular surgery of the Second Affiliated Hospital of Zhengzhou University were diagnosed as AAD through direct digital angiography(DSA), magnetic resonance angiography(MRA), CT angiography(CTA)or transesophageal echocardiography(TEE). 48 hospitalized patients at the same time interval who were diagnosed with acute coronary syndrome(ACS)were included as a control group. All patients took blood at the time of admission when D-dimer concentration was tested. Statistics were used for data analysis. Results D-dimer concentration in AAD group was significantly higher than in the ACS group(P<0.05); In the medical diagnosis of AAD, D-dimer levels in deaths were much higher than in the survival patients(P<0.05). Conclusions D-dimer test, as the index of early AAD the negative test results for the diagnosis of AAD exclusion are of great help to assess the prognosis of patients with high and low concentrations of D-dimer and lesions range estimates are also instructive.

Key words: D-dimer, Acute aortic dissection, Acute coronary syndrome