Role of an elevated D-dimer cut-off value for the prognosis of lung cancer

doi:10.3969/j.issn.1673-8640.2020.08.005

Abstract

Abstract:

Objective To investigate the role of an elevated D-dimer（DD） cut-off value for the prognosis of lung cancer. Methods The clinical and laboratory data of 153 patients with lung cancer were studied retrospectively. Carcinoembryonic antigen（CEA）,cytokeratin-19 fragment（CYFRA21-1）,lactate dehydrogenase（LDH）,squamous cell carcinoma antigen（SCC-Ag） and DD were determined before chemotherapy or surgery,and the results were analyzed statistically. Results There was no statistical significance for overall survival rate between different sex,age,CEA,CYFRA21-1,LDH and DD（P>0.05）. The overall survival rate in high DD（≥981 ng/mL） group was lower than that in normal DD（<981 ng/mL） group（P<0.05）. Conclusions The elevated DD cut-off value to 981 ng/mL is beneficial to prognosis prediction in lung cancer.

Key words: Lung cancer, D-dimer, Cut-off value, Overall survival

CLC Number:

R446.1

LIU Qin, CHEN Chong, YUE Chao. Role of an elevated D-dimer cut-off value for the prognosis of lung cancer[J]. Laboratory Medicine, 2020, 35(8): 763-766.

Figures/Tables 3

References 17

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