肠道菌群与IL-6/gp130信号通路在急性胰腺炎发病机制中的研究进展

doi:10.3969/j.issn.1673-8640.2021.05.021

摘要/Abstract

摘要：

急性胰腺炎是临床常见急腹症之一,以胰腺局部炎症反应为主要特征,伴或不伴有其他器官功能改变。肠道菌群失衡与炎症反应的激活是急性胰腺炎发病的两大危险因素。文章对近年来肠道菌群与白细胞介素6（IL-6）/糖蛋白130（gp130）炎症信号通路在急性胰腺炎发病机制中的研究进展进行综述。

关键词: 肠道菌群, 炎症, 白细胞介素6, 糖蛋白130, 急性胰腺炎

Abstract:

Acute pancreatitis is one of the most common acute abdominal diseases. It is characterized by local inflammation of the pancreas with or without changes in the function of other organs. Dysbacteriosis and activation of inflammatory response are risk factors for acute pancreatitis. This review focuses on recent advances in the study of intestinal microbiota and interleukin-6（IL-6）/glycoprotein 130（gp130） inflammatory signaling pathway in the pathogenesis of acute pancreatitis.

Key words: Intestinal microbiota, Inflammation, Interleukin-6, Glycoprotein 130, Acute pancreatitis

中图分类号:

R446.5

肖樱艳, 崔艳, 李艳. 肠道菌群与IL-6/gp130信号通路在急性胰腺炎发病机制中的研究进展[J]. 检验医学, 2021, 36(5): 565-568.

XIAO Yingyan, CUI Yan, LI Yan. Research progress of intestinal microbiota and IL-6/gp130 signaling pathway in acute pancreatitis pathogenesis[J]. Laboratory Medicine, 2021, 36(5): 565-568.

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