关键词: 补体C1q, 参考区间, 免疫透射比浊法

Abstract:

Objective To establish the reference ranges of serum complement C1q among apparently healthy adults in Taizhou,and to investigate the relationship between complement C1q and other parameters. Methodse A total of 463 apparently healthy adults were enrolled in Taizhou Central Hospital from February 2016 to March 2016,including 240 males and 223 females. Serum complement C1q was determined by turbidimetric inhibition immunoassay. The reference ranges were expressed by bilateral 95% confidence interval of normal distribution. Results The levels of complement C1q were expressed as normal distribution. The level of complement C1q in females [（210.3±25.6） mg/L] was higher than that in males [（197.8±26.1） mg/L]（P<0.01）. Complement C1q had positive correlations with globulin,white blood cell （WBC）,total cholesterol （TC） （r>0,P<0.05）,and had negative correlations with creatinine （Cr） and hemoglobin （Hb）（r<0,P<0.05）. There was no correlation with ages （P>0.05）. Conclusions The level of complement C1q in healthy adults has difference between males and females. The reference ranges of complement C1q should be established for males and females in Taizhou respectively.

Key words: Complement C1q, Reference ranges, Turbidimetric inhibition immunoassay