关键词: 维生素A, 25-羟基维生素D, 维生素E, 维生素不足, 维生素缺乏

Abstract:

Objective To investigate the levels of serum vitamin A（Vit A）,25-hydroxyvitamin D [25（OH）D] and vitamin E（Vit E） of children under 6 years old in Jiamusi,and to provide a reference for the reasonable supplementation of Vit A,vitamin D（Vit D） and Vit E and preventing from related diseases. Methods According to ages,5 169 children were classified into 6 groups,<1-year-old group（732 cases）,1-year-old group（831 cases）,2-year-old group （693 cases）,3-year-old group（1 164 cases）,4-year-old group （1 008 cases） and 5-year-old group（741 cases）. After achieving questionnaires,the venous blood was extracted. The levels of Vit A and Vit E were determined by high-performance liquid chromatography,and the level of 25（OH）D was determined by high-performance liquid chromatography tandem mass spectrometry. Results The level of Vit A was（0.28±0.087）mg/L. The insufficiency rate was 54.09%,and the deficiency rate was 13.46%. There was statistical significance with different ages （F=4.370,P=0.001）. The minimal level of Vit A was （0.25±0.071）mg/L in <1-year-old group,the insufficiency rate was 61.48%,and the deficiency rate was 19.67%. The level of 25（OH）D was （24.20±9.97）ng/mL,the insufficiency rate was 18.57%,and the deficiency rate was 17.99%. With the increasing of ages,the levels of 25（OH）D decreased. The average level of Vit E was（8.68±2.49）mg/L,the insufficiency rate was 21.53%,and the deficiency rate was 0.58%. With the increasing of ages,the level of Vit E had a decreasing tendency. Conclusions The nutritional status of Vit A and 25（OH）D of children under 6 years old is not optimistic in Jiamusi. It is necessary to determine and give reasonable supplementation of vitamin for high-risk subjects in order to prevent from vitamin deficiency disorder. The nutritional status of Vit E is relatively good.

Key words: Vitamin A, 25-Hydroxyvitamin D, Vitamin E, Vitamin insufficiency, Vitamin deficiency