糖类抗原及其相关分子在肿瘤诊断中的研究进展

doi:10.3969/j.issn.1673-8640.2014.09.001

检验医学 ›› 2014, Vol. 29 ›› Issue (9): 873-876.DOI: 10.3969/j.issn.1673-8640.2014.09.001

• 肿瘤免疫专题 • 下一篇

糖类抗原及其相关分子在肿瘤诊断中的研究进展

高锋

上海交通大学附属第六人民医院检验科,上海 200233

收稿日期:2014-03-20 出版日期:2014-09-30 发布日期:2014-09-25
作者简介:高锋,男,1962年生,博士,研究员,主要从事肿瘤免疫学研究

The research progress of carbohydrate antigens and their relative molecules in tumor diagnosis

GAO Feng

Department of Clinical Laboratory, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China

Received:2014-03-20 Online:2014-09-30 Published:2014-09-25

摘要/Abstract

摘要：

糖基化变更是癌细胞的普遍特征。某些类型的聚糖结构被公认为是肿瘤发展的标志物,但现有分子常不能满足肿瘤早期诊断、预后和转移判断的迫切需求。近年来,糖类抗原(CA)及其相关分子在肿瘤诊断中的研究取得很多进展。因此应根据现有研究基础建立新的CA及其相关分子的肿瘤标志物及多参数联合检测方法,使之更好地服务于临床诊断。

关键词: 糖类抗原, 肿瘤诊断, 多参数分析

Abstract:

Glycosylation changes are the common characteristics of cancer cells. Some types of glycan structures are recognized as the markers of tumor development, but the current molecules cannot regularly meet the pressing needs of tumor early diagnosis, prognosis and metastasis judgment. In recent years, a remarkable progress has been made in the yield of carbohydrate antigens(CA) and their relative molecules in tumor diagnosis. In order to serve the clinical needs better, new tumor markers of CA and their relative molecules, together with multi-parameter analysis, should be established.

Key words: Carbohydrate antigen, Tumor diagnosis, Multi-parameter analysis

中图分类号:

R446.62

高锋. 糖类抗原及其相关分子在肿瘤诊断中的研究进展[J]. 检验医学, 2014, 29(9): 873-876.

GAO Feng. The research progress of carbohydrate antigens and their relative molecules in tumor diagnosis[J]. , 2014, 29(9): 873-876.

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糖类抗原及其相关分子在肿瘤诊断中的研究进展

The research progress of carbohydrate antigens and their relative molecules in tumor diagnosis

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