Abstract: Objective To investigate the relations of red blood cell distribution width（RDW） and serum total bilirubin（TB） with coronary heart disease（CHD） and its coronary artery lesion branches and Gensini score. Methods A total of 200 CHD patients undergoing coronary angiography were enrolled as CHD group,taking positive coronary angiography（stenosis of major vessels ≥ 50%） as diagnostic standard of CHD. Totally,100 healthy subjects were enrolled as control group. The levels of RDW and TB were determined,and the relations of total cholesterol（TC）,triglyceride（TG）,high-density lipoprotein cholesterol（HDL-C）,low-density lipoprotein cholesterol（LDL-C）,cardiac troponin I（cTnI）,myoglobin（MYO）,B-type natriuretic peptide（BNP）and creatinine kinase-MB isoenzyme（CK-MB）with RDW and TB were analyzed by. Statistical analysis was used to analyze the difference between RDW and TB in patients with different coronary artery lesion branches. Spearman correlation analysis was used to analyze the relation between the levels of RDW and TB and Gensini score. Results RDW was higher in CHD group than that in control group（P<0.05）,and the level of TB was decreased（P<0.05）. In CHD group,RDW was negatively correlated with HDL-C（r=-0.677,P<0.05） and positively correlated with cTnI（r=0.196,P<0.01）,and TB was positively correlated with HDL-C（r=0.525,P<0.05）and negatively correlated with cTnI（r=-0.118,P<0.05）. RDW in patients with single-,double- and triple-branch coronary artery lesions increased in turn（P<0.01）,and TB decreased in turn（P<0.01）. RDW level was positively correlated with Gensini score（r=0.437,P<0.05）. TB level was negatively correlated with Gensini score （r=-0.385,P<0.05）. Conclusions RDW and TB are correlated with CHD and the severity of coronary artery lesions,and they play roles in the evaluation of CHD risk and prognosis.

Key words: Red blood cell distribution width, Total bilirubin, Coronary heart disease, Coronary artery lesion, Gensini score