Correlation of serum bilirubin and CK-MB mass with age in newborns

doi:10.3969/j.issn.1673-8640.2020.10.013

Abstract

Abstract:

Objective To investigate the relationship between total bilirubin（TB）,direct bilirubin（DBil）and creatine kinase isoenzyme MB mass（CK-MB mass）with age in newborns. Methods A total of 106 newborns aged 0-28 d were classified into 3 groups according to birth days,which included ≤5 d group（48 cases）,>5-≤10 d group（32 cases） and >10-≤28 d group（26 cases）. Spearman correlation analysis was used to evaluate the correlation between each index and age. Results Serum TB level in >5-≤10 d group was higher than those in ≤5 d and >10-≤28 d groups（P<0.001）,and DBil level in >10-≤28 d group was higher than those in ≤5 d and >5-≤10 d groups（P<0.001）,while serum CK-MB mass in ≤5 d,>5-≤10 d and >10-≤28 d groups was decreased in turn（P<0.05）. There was no correlation between TB and age（r=0.038,P>0.05）,DBil was correlated positively with age（r=0.469,P<0.05）,and there was a negative correlation between CK-MB mass and age（r =-0.559,P<0.05）. Conclusions DBil and CK-MB mass in newborns have a certain relationship with age.

Key words: Total bilirubin, Direct bilirubin, Creatine kinase isoenzyme MB mass, Newborn

CLC Number:

R446.1

ZHENG Gaoming, SU Xiaoru. Correlation of serum bilirubin and CK-MB mass with age in newborns[J]. Laboratory Medicine, 2020, 35(10): 1025-1027.

Figures/Tables 2

References 12

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组别	例数	TB/（μmol/L）	DBil/（μmol/L）	CK-MB mass/（ng/mL）
≤5 d组	48	171.40（115.75~215.60）	11.58（9.95~13.55）	12.19（8.40~17.04）
>5~≤10 d组	32	217.00（186.70~270.75）^**	12.15（10.97~13.90）	10.16（6.70~12.58）^*
>10~≤28 d组	26	142.60（93.50~186.70）^##	15.50（11.90~17.20）^**##	6.45（5.49~7.33）^**#

组别	例数	TB/（μmol/L）	DBil/（μmol/L）	CK-MB mass/（ng/mL）
≤5 d组	48	171.40（115.75~215.60）	11.58（9.95~13.55）	12.19（8.40~17.04）
>5~≤10 d组	32	217.00（186.70~270.75）^**	12.15（10.97~13.90）	10.16（6.70~12.58）^*
>10~≤28 d组	26	142.60（93.50~186.70）^##	15.50（11.90~17.20）^**##	6.45（5.49~7.33）^**#

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