Analysis on the laboratory examination results of 5 cases of diclonal multiple myeloma

doi:10.3969/j.issn.1673-8640.2019.08.008

Abstract

Abstract:

Objective To analyze the clinical and laboratory examination characteristics of diclonal multiple myeloma ,and to improve the detection rate of diclonal multiple myeloma. Methods The clinical data were collected from 5 cases of diclonal multiple myeloma in Huazhong University of Science and Technology Tongji Medical College Tongji Hospital from 2014 to 2017. Results In the 5 cases of diclonal multiple myeloma,there were 2 cases of IgG-IgA and 3 cases of IgG-IgG. Two cases were treated and changed into monoclonal multiple myeloma. Conclusions The clinical characteristics of diclonal multiple myeloma are lacking in specificity. Patients with diclonal multiple myeloma must be fully determined in laboratories to improve the detection rate of diclonal multiple myeloma.

Key words: Diclonal multiple myeloma, Immune-fixation electrophoresis, Immunoglobulin

CLC Number:

R446.1

ZHENG Wei, LU Jie, HAO Aijun, ZHANG Yinhui. Analysis on the laboratory examination results of 5 cases of diclonal multiple myeloma[J]. Laboratory Medicine, 2019, 34(8): 710-716.

Figures/Tables 6

References 13

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病例	分型	性别	年龄	IgG（g/L）	IgM（g/L）	IgA（g/L）	总к轻链（g/L）	总λ轻链（g/L）
1	IgA-λ/IgG-λ	女	50	5.8	0.44	15.20	1.05	4.33
2	IgA-λ/IgG-λ	女	56	9.5	0.10	62.70	0.28	15.00
3	IgG-λ/IgG-λ	男	78	32.9	0.08	0.15	0.82	81.40
4	IgG-λ/IgG-κ	男	53	31.9	0.06	0.13	7.50	79.90
5	IgG-λ/IgG-κ	男	48	29.9	0.10	0.16	10.20	67.30
病例	总κ轻链与λ轻链比值	总蛋白（g/L）	白蛋白（g/L）	血红蛋白（g/L）	尿素（mmol/L）	肌酐（mmol/L）	钙（mmol/L）
1	0.242	77.6	36.7	99	4.86	98.5	2.33
2	0.019	78.1	40.2	121	3.09	90.8	2.34
3	0.010	119.0	38.5	86	4.45	87.5	2.43
4	0.094	122.0	36.5	89	8.15	212.0	2.56
5	0.150	102.5	37.9	90	4.45	101.2	2.43

病例	分型	性别	年龄	IgG（g/L）	IgM（g/L）	IgA（g/L）	总к轻链（g/L）	总λ轻链（g/L）
1	IgA-λ/IgG-λ	女	50	5.8	0.44	15.20	1.05	4.33
2	IgA-λ/IgG-λ	女	56	9.5	0.10	62.70	0.28	15.00
3	IgG-λ/IgG-λ	男	78	32.9	0.08	0.15	0.82	81.40
4	IgG-λ/IgG-κ	男	53	31.9	0.06	0.13	7.50	79.90
5	IgG-λ/IgG-κ	男	48	29.9	0.10	0.16	10.20	67.30
病例	总κ轻链与λ轻链比值	总蛋白（g/L）	白蛋白（g/L）	血红蛋白（g/L）	尿素（mmol/L）	肌酐（mmol/L）	钙（mmol/L）
1	0.242	77.6	36.7	99	4.86	98.5	2.33
2	0.019	78.1	40.2	121	3.09	90.8	2.34
3	0.010	119.0	38.5	86	4.45	87.5	2.43
4	0.094	122.0	36.5	89	8.15	212.0	2.56
5	0.150	102.5	37.9	90	4.45	101.2	2.43

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