lncRNA SNP在结直肠癌易感性预测和预后评估中的应用

doi:10.3969/j.issn.1673-8640.2023.12.020

摘要/Abstract

摘要：

结直肠癌是世界上最常见的癌症之一。长链非编码RNA（lncRNA）单核苷酸多态性（SNP）在结直肠癌发生、发展过程中起着至关重要的作用。lncRNA SNP作为新的、低侵入性的生物标志物对结直肠癌的易感性预测、预后评估、病理分级判定、药物敏感性监测具有一定价值。

关键词: 长链非编码RNA, 单核苷酸多态性, 生物标志物, 结直肠癌

Abstract:

Colorectal cancer is one of the most common cancers in the world. Long non-coding RNA（lncRNA） single nucleotide polymorphisms（SNP） play roles in the occurrence and development of colorectal cancer. As a new and less invasive biomarker，lncRNA SNP has a certain value in predicting susceptibility，assessing prognosis，determining pathologic grades and monitoring drug susceptibility of colorectal cancer.

Key words: Long non-coding RNA, Single nucleotide polymorphism, Biomarker, Colorectal cancer

中图分类号:

R446.1

周福荣, 李龑杼, 刘勇敢. lncRNA SNP在结直肠癌易感性预测和预后评估中的应用[J]. 检验医学, 2023, 38(12): 1206-1210.

ZHOU Furong, LI Yanzhu, LIU Yonggan. Application of lncRNA SNP in colorectal cancer susceptibility prediction and prognosis assessment[J]. Laboratory Medicine, 2023, 38(12): 1206-1210.

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