检验医学 ›› 2021, Vol. 36 ›› Issue (12): 1283-1286.DOI: 10.3969/j.issn.1673-8640.2021.012.018

• 综述与讲座 • 上一篇    下一篇

血小板线粒体功能研究进展

赵小霞   

  1. 南开大学附属第四中心医院检验科,天津 300140
  • 收稿日期:2020-10-03 出版日期:2021-12-30 发布日期:2021-12-29
  • 作者简介:赵小霞,女,1979年生,博士,副主任技师,主要从事临床血栓与止血检测工作。

Research progress of mitochondria in platelets

ZHAO Xiaoxia   

  1. Department of Clinical Laboratory,the Fourth Central Hospital Affiliated to Nankai University,Tianjin 300140,China
  • Received:2020-10-03 Online:2021-12-30 Published:2021-12-29

摘要:

线粒体对无细胞核的血小板的生理功能及生物活性具有重要作用。文章对线粒体在血小板能量代谢和三磷酸腺苷(ATP)的产生、活化、2周凋亡和系统性疾病中的病理生理作用进行综述,以期为进一步的学术研究和临床治疗提供参考。

关键词: 血小板, 线粒体, 能量代谢, 生理作用, 病理作用

Abstract:

Platelet is nuclear-free,and mitochondria play roles in it. This review focuses on the mitochondria in energy metabolism,adenosine triphosphate(ATP) production,activation and apoptosis of platelet and the pathophysiologic role in systemic diseases,which provides a reference for further research and clinical treatment.

Key words: Platelet, Mitochondrion, Energy metabolism, Physiological role, Pathophysiologic role

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