幽门螺杆菌检测方法的发展与比较

doi:10.3969/j.issn.1673-8640.2018.01.016

摘要/Abstract

摘要：

幽门螺杆菌（Hp）与许多胃肠道疾病关系密切,因此对其精确检测尤为重要。现有许多用于检测Hp的侵入性或非侵入性试验可供临床选择：侵入性试验一般通过内镜获取组织样本后进行检测,包括组织学检查、分离培养与药物敏感性试验、快速脲酶试验和分子生物学检测等;非侵入性试验包括尿素呼气试验（UBT）、粪便Hp抗原检测（SAT）以及Hp血清学检测。许多试验还可用于检测Hp的毒力、耐药性以及监测胃肠道肿瘤或癌前病变。文章回顾了现在常用的Hp检测方法的发展及其应用,以便为临床诊治Hp感染提供依据。

关键词: 幽门螺杆菌, 检测方法, 侵入性, 非侵入性

Abstract:

：Many gastroduodenal diseases are associated with Helicobacter pylori （HP） infection,so accurate diagnosis of Hp infection is needed. Nowadays,several invasive and non-invasive tests are available for the detection of Hp. Endoscopy is used to collect specimens for invasive test,including endoscopic image,histology,culturing,rapid urease test and molecula. Methods . Non-invasive tests include urea breath test,stool antigen test and serological test. Some tests can analyze virulence and drug resistance as well. This review focuses on the development and application of Hp detection,in order to provide a reference for clinical application.

Key words: Helicobacter pylori, Detection method, Invasion, Non-invasion

中图分类号:

R446.5

崔俊华, 李懿皞, 周佳烨, 吴炯, 郭玮, 潘柏申. 幽门螺杆菌检测方法的发展与比较[J]. 检验医学, 2018, 33(1): 82-87.

CUI Junhua, LI Yihao, ZHOU Jiaye, WU Jiong, GUO Wei, PAN Baishen. Development and comparison of Helicobacter pylori detection[J]. Laboratory Medicine, 2018, 33(1): 82-87.

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