检验医学 ›› 2018, Vol. 33 ›› Issue (8): 764-767.DOI: 10.3969/j.issn.1673-8640.2018.08.021

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使用抗菌药物对婴幼儿肠道微生态的影响

苏思婷, 温洪宇, 袁振亚, 王秀颖, 王国振, 俞晨洁   

  1. 江苏师范大学生命科学学院,江苏 徐州 221116
  • 收稿日期:2017-08-22 出版日期:2018-08-10 发布日期:2018-09-07
  • 作者简介:null

    作者简介:苏思婷,女,1997年生,主要从事细菌耐药机制研究。

  • 基金资助:
    江苏省大学生创新创业训练计划项目(201710320106X);2017年度徐州市推动科技创新项目(KC17082);江苏师范大学生命科学学院“十二五”专业综合改革试点项目(239)

Influence of antibiotic use on intestinal microecology of infants

SU Siting, WEN Hongyu, YUAN Zhenya, WANG Xiuying, WANG Guozhen, YU Chenjie   

  1. School of Life Science,Jiangsu Normal University,Xuzhou 221116,Jiangsu,China
  • Received:2017-08-22 Online:2018-08-10 Published:2018-09-07

摘要:

人体肠道微生态中含有大量细菌,这些细菌对于人类健康具有重要的作用。目前,抗菌药物已经成为最常用的药物之一。抗菌药物的使用增加了某些疾病的患病风险,尤其是婴幼儿时期使用抗菌药物会导致肠道微生态失衡。近年来,围绕抗菌药物对肠道微生态的影响开展的研究越来越多。文章就抗菌药物给婴幼儿肠道微生态带来的影响作一综述。

关键词: 肠道微生态, 婴幼儿, 耐药性, 耐药基因

Abstract:

Human intestinal microecology has a vast number of bacteria,which plays a critical role in human health. At present,it is generally accepted that antibiotics have been one of the most common drugs in the world,and antibiotic use is associated with increasing risk for several diseases. Antibiotic use during infancy will induce imbalance in intestinal microecology,which is called dysbiosis. In the recent years,more and more researches have been known about the influence of antibiotics on intestinal microecology of infants. This review summarizes the effects of antibiotics on intestinal microecology of infants.

Key words: Intestinal microecology, Infants, Drug resistance, Drug resistance gene

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