检验医学 ›› 2016, Vol. 31 ›› Issue (9): 735-738.DOI: 10.3969/j.issn.1673-8640.2016.09.001

• 深部真菌的耐药性及耐药机制专题 •    下一篇

深部真菌的耐药性及其耐药机制研究

赵虎   

  1. 复旦大学附属华东医院检验科, 上海 200040
  • 收稿日期:2016-07-19 出版日期:2016-09-30 发布日期:2016-10-11
  • 作者简介:null

    作者简介:赵 虎,男,1962年生,博士,教授,主要从事临床微生物学研究。

Drug resistance of invasive fungi and its mechanisms

ZHAO Hu   

  1. Department of Clinical Laboratory,Huadong Hospital,Fudan University,Shanghai 200040,China
  • Received:2016-07-19 Online:2016-09-30 Published:2016-10-11

摘要:

本期“深部真菌的耐药性及耐药机制”专题汇集了4篇论著和1篇综述,阐述了白念珠菌、烟曲霉和新生隐球菌的耐药性及其耐药机制。随着抗真菌药物的大力应用,真菌的耐药性不断上升,研究真菌的耐药机制并探讨新抗真菌药物的作用靶点,可为新抗真菌药物研发和临床抗真菌治疗提供参考依据,这有着重要的临床意义。

关键词: 深部真菌, 白念珠菌, 烟曲霉, 新生隐球菌, 耐药性, 耐药机制

Abstract:

A total of 4 original articles and 1 review about the drug resistance of invasive fungi and its mechanisms are collected for this special topic. The original articles and review describe the drug resistance and mechanisms of Candida albicans,Aspergillus fumigatus and Cryptococcus neoformans. While antifungal agents are widely used in recent years,the drug resistance of fungi increases gradually. It is useful to study the drug resistance mechanism of fungi and the new targets for antifungal agents. It can provide a reference for the research and development of new antifungal agents and the treatment with antifungal agents.

Key words: Invasive fungi, Candida albicans, Aspergillus fumigatus, Cryptococcus neoformans, Drug resistance, Drug resistance mechanisms

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