检验医学 ›› 2015, Vol. 30 ›› Issue (7): 694-696.DOI: 10.3969/j.issn.1673-8640.2015.07.007

• 临床应用研究·论著 • 上一篇    下一篇

广州番禺地区儿童总钙和25-羟基维生素D检测结果分析

肖钘1, 何金花1, 黎毓光1, 韩泽平1, 胡淑芬1, 黄惠2   

  1. 1.广州市番禺区中心医院检验科,广东 广州 511400
    2.南方医科大学检验系,广东 广州 510515
  • 收稿日期:2014-09-10 出版日期:2015-07-30 发布日期:2015-08-28
  • 作者简介:null

    作者简介:肖 钘,男,1983年生,学士,主管技师,主要从事临床检验工作。

Analysis on the results of calcium and 25-hydroxy vitamin D of children in Panyu, Guangzhou

XIAO Xing1, HE Jinhua1, LI Yuguang1, HAN Zeping1, HU Shufen1, HUANG Hui2   

  1. 1. Department of Clinical Laboratory, Panyu Central Hospital, Guangdong Guangzhou 511400, China
    2. Department of Laboratory Medicine, Southern Medical University, Guangdong Guangzhou 510515, China
  • Received:2014-09-10 Online:2015-07-30 Published:2015-08-28

摘要: 目的

统计广州市番禺地区儿童总钙和25-羟基维生素D[25(OH)D]水平并进行分析,为以后该地区儿童保健提供参考依据。

方法

使用原子吸收光谱仪和电化学发光仪检测1 902名儿童总钙和25(OH)D水平。将受检儿童按年龄不同分为5个年龄组:婴儿组(1~12个月,817名)、幼儿组(1~2岁,599名)、学龄前组(3~6岁,291名)、学龄期组(7~11岁,167名)、青春发育期组(12~18岁,28名)。在按年龄分组的基础上再按性别分成男、女两组。对各组总钙和25(OH)D水平进行统计分析。

结果

广州番禺地区儿童总钙水平为(1.72±0.19)mmol/L,25(OH)D 水平为(39.12±11.26)ng/mL,两者均随年龄的增长呈下降趋势。按年龄分组比较显示婴儿组总钙及25(OH)D水平均明显高于其余4组(P均<0.05);幼儿组总钙水平明显高于学龄前组及学龄期组(P均<0.05),25(OH)D水平明显高于学龄前组、学龄期组及青春发育期组;学龄前组总钙及25(OH)D水平均高于学龄期组(P均<0.05)。男、女性儿童总钙和25(OH)D水平差异均无统计学意义(P均>0.05)。总钙和25(OH)D呈正相关[相关系数(r)=0.221,P<0.05,线性方程为Y总钙=0.004X25(OH)D+1.573]。

结论

番禺地区儿童血液总钙和25(OH)D水平偏低。建议学校和家长能督促儿童及时、合理的补钙。

关键词: 总钙, 25-羟基维生素D, 儿童, 原子吸收光谱法, 电化学发光法

Abstract: Objective

To analyze statistically the levels of calcium and 25-hydroxy vitamin D[25(OH)D] of children in Panyu, Guangzhou, in order to provide reference for child health care.

Methods

The levels of calcium and 25(OH)D were determined by atomic absorption spectrometer and electrochemiluminescence immunoassay from 1 902 children. The children were classified into 5 groups according to age, infancy group(1-12 months, 817 cases), toddler age group(1-2 years, 599 cases), preschool age group(3-6 years, 291 cases), school age group(7-11 years,167 cases) and adolescence group(12-18 years, 28 cases). Based on different age groups, each group was subclassified by male and female. The calcium and 25(OH)D levels were analyzed statistically.

Results

The average level of calcium was (1.72±0.19) mmol/L, and the average level of 25(OH)D was (39.12±11.26) ng/mL, and the levels of calcium and 25(OH)D had downward trend with the increasing of age. The levels of calcium and 25(OH)D in infancy group were higher than those in the other 4 groups(P<0.05). The levels of calcium in toddler age group was higher than those in preschool age group and school age group (P<0.05). The levels of 25(OH)D in toddler age group was higher than those in preschool age group, school age group and adolescence group. The levels of calcium and 25(OH)D in preschool age group were higher than those in school age group(P<0.05). There was no statistical significance for calcium and 25(OH)D levels with different sex (P>0.05). Calcium and 25(OH)D were in positive correlation [correlation coefficient (r)=0.221,P<0.05]. Linear equation was Ycalcium=0.004X25(OH)D+1.573.

Conclusions

The levels of calcium and 25(OH)D are not high among Panyu children. The related schools and parents should supervise their children with calcium supplement rationly.

Key words: Calcium, 25-hydroxy vitamin D, Child, Atomic absorption spectrometer, Electrochemiluminescence immunoassay

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