心肌肌钙蛋白检测在儿科心脏受累相关疾病中的临床应用

doi:10.3969/j.issn.1673-8640.2023.06.002

摘要/Abstract

摘要：

心肌肌钙蛋白（cTn）是心肌损伤敏感且特异的标志物。在成人中，cTn主要用于急性、慢性心肌损伤的诊断和危险分层。与成人不同，儿童患者心肌梗死和冠心病等心脏相关疾病的患病率较低，常见的心脏相关疾病为心肌炎、心包炎、先天性心脏病（CHD）等。同时，感染相关疾病、创伤、抗肿瘤药物等可累及心脏。cTn在儿童患者中具有一定的临床价值，但临床解读不尽相同。文章就cTn检测在儿科心脏受累相关疾病中的临床应用进行综述。

关键词: 心肌肌钙蛋白, 儿童, 心肌损伤, 心血管疾病, 非心血管疾病

Abstract:

Cardiac troponin （cTn） is a sensitive and specific marker of myocardial injury. In adults，cTn is widely used in the diagnosis of acute and chronic myocardial injury and risk stratification. Being different from adults，the prevalence of myocardial infarction and coronary heart diseases in children is low，and myocarditis，pericarditis and congenital heart disease（CHD） are common in children. Cardiac injury can occurred secondary to infection，trauma and cancer drug therapy in children. The indicator，cTn，is useful in all these clinical conditions with proper interpretations based on the pediatric patients. This review focuses on the clinical application of cTn determination in children.

Key words: Cardiac troponin, Children, Myocardial injury, Cardiovascular disease, Non-cardiovascular disease

中图分类号:

R446.1

杨琼, 徐芬, 蔺亚晖. 心肌肌钙蛋白检测在儿科心脏受累相关疾病中的临床应用[J]. 检验医学, 2023, 38(6): 510-517.

YANG Qiong, XU Fen, LIN Yahui. Clinical application of cardiac troponin determination in pediatric cardiac involvement related diseases[J]. Laboratory Medicine, 2023, 38(6): 510-517.

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