Drug resistance genes of Candida albicans to azoles and their regulation mechanisms

doi:10.3969/j.issn.1673-8640.2016.09.002

Abstract

Abstract:

Candida albicans is a conditionally pathogenic fungus in human. With azoles being widely applied for a long time,the clinical isolates of Candida albicans against azoles gradually increase. The clinical treatment of Candida albicans has become a thorny issue. The drug resistance genes of Candida albicans and regulation mechanisms are reviewed for finding new therapeutic targets and developing new antifungal agents at the level of transcriptional regulation.

Key words: Candida albicans, Azoles, Drug resistance genes, Regulation mechanisms

CLC Number:

R379.4

WU Yongqin, YING Chunmei. Drug resistance genes of Candida albicans to azoles and their regulation mechanisms[J]. Laboratory Medicine, 2016, 31(9): 739-743.

Figures/Tables 1

References 35

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