Abstract:

Objective To analyze the detection results of 7 kinds of common respiratory viruses,and to provide a reference for the diagnosis and treatment of pediatric respiratory tract infection. Methods The nasopharynx swab or lavage fluid samples were collected from 14 741 hospitalized children with respiratory tract infection from March 2016 to February 2018 in Xiamen Children's Hospital. Influenza A（IFA）,influenza B（IFB）,respiratory syncytial virus（RSV）,adenovirus（ADV）and parainfluenza 1（PIV1）,parainfluenza 2（PIV2）,parainfluenza 3（PIV3）were detected by direct immunofluorescence method. The epidemic characteristics of different ages and sex were evaluated. Results Among the 14 741 cases,3 693 cases were positive for the 7 kinds of common respiratory viruses,and the positive rate was 25.05%. The positive rate was 15.98% in 2 355 male children,and the positive rate was 9.08% in 1 338 female children. The positive rates of children infected with various respiratory viruses were RSV 15.15%,ADV 3.49%,PIV3 3.12%,IFA 1.08%,IFB 1.01%,PIV1 0.91%,PIV2 0.29%,respectively. There was statistical significance for ADV and RSV in infant group（<1-year-old） and IFB in preschool group（6-<12-year-old）（P<0.05）. There was no statistical significance for the other groups（P>0.05）. Conclusions The main pathogens in children with respiratory tract infection of pediatric children are RSV,ADV and PIV3,and there were differences among different viruses in different seasons,sex and ages in Xiamen. Prevention and control measures should be taken.

Key words: Respiratory virus, Respiratory tract infection, Direct immunofluorescence, Children