Laboratory Medicine ›› 2023, Vol. 38 ›› Issue (6): 510-517.DOI: 10.3969/j.issn.1673-8640.2023.06.002

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Clinical application of cardiac troponin determination in pediatric cardiac involvement related diseases

YANG Qiong, XU Fen, LIN Yahui()   

  1. Experimental Diagnostic Center,National Center for Cardiovascular Diseases, Fuwai Hospital of Chinese Academy of Medical Sciences,Beijing Key Laboratory of Molecular Diagnosis of Cardiovascular Diseases,Beijing 100037,China
  • Received:2022-06-20 Revised:2023-01-09 Online:2023-06-30 Published:2023-08-22

Abstract:

Cardiac troponin (cTn) is a sensitive and specific marker of myocardial injury. In adults,cTn is widely used in the diagnosis of acute and chronic myocardial injury and risk stratification. Being different from adults,the prevalence of myocardial infarction and coronary heart diseases in children is low,and myocarditis,pericarditis and congenital heart disease(CHD) are common in children. Cardiac injury can occurred secondary to infection,trauma and cancer drug therapy in children. The indicator,cTn,is useful in all these clinical conditions with proper interpretations based on the pediatric patients. This review focuses on the clinical application of cTn determination in children.

Key words: Cardiac troponin, Children, Myocardial injury, Cardiovascular disease, Non-cardiovascular disease

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