Abstract:

In the recent years，an increasing number of studies have confirmed the diagnostic value and clinical application prospects of cardiac markers in different diseases，such as myocarditis，cardiomyopathy，congenital heart disease（CHD） and heart failure among children. In addition，it has made new progress in judging cardiac function，the degree of myocardial injury，the occurrence of complications and the effect of diagnosis and treatment of immune-related and other systemic diseases. Children's tissues and organs are still in growth and development stage，there are differences in the determination results of cardiac markers in children with different ages，especially in newborns，which makes the interpretation of determination reports more challenging. Therefore，future researches should focus on new analytical methods，the establishment of biological reference intervals for different ages and more evidence-based research in the diagnosis and treatment of children. Related guidelines or expert consensus should be issued to promote the clinical standard application of cardiac marker determination results in children.

Key words: Children, Cardiac marker, Cardiac troponin, B-type natriuretic peptide