Research progress of exosomal miRNA in pancreatic cancer

doi:10.3969/j.issn.1673-8640.2018.011.017

Abstract

Abstract:

Exosomes are sorts of small extracellular vesicles ranging approximately from 30 nm to 100 nm in diameter,which can serve as carriers transporting microRNA（miRNA）,protein and others to target cells by means of cell membrane fusion and cell swallowing,further mediating cell communication and regulating cell physiological function. In recent years,the related researches have found that exosomal miRNA plays a role in the occurrence,development and clinical diagnosis of pancreatic cancer（PC）,which is expected to provide new ideas for the diagnosis and treatment of PC. In this review,the role of exosomal miRNA in PC will be introduced based on domestic and overseas research status.

Key words: Pancreatic cancer, Exosome, MicroRNA

CLC Number:

R446.1

CHEN Jia, WANG Jian, JIN Wei, CHEN Xudong, HU Xiaobo. Research progress of exosomal miRNA in pancreatic cancer[J]. Laboratory Medicine, 2018, 33(11): 1049-1052.

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