Abstract:

Objective To analyze the results of respiratory tract virus determination among children in Suzhou from 2011 to 2015.Methods Direct immunofluorescent method was used to determine 7 common respiratory tract viruses,including adenovirus（ADV）,influenza virus A（IVA）,influenza virus B（IVB）,parainfluenza virus 1（PIV1）,parainfluenza virus 2（PIV2）,parainfluenza virus 3（PIV3） and respiratory syncytial virus（RSV）. The positive rates and mixed viral infection rates were evaluated. Results A total of 2 151 children with respiratory tract infection were enrolled,and the overall positive rate for the 7 common respiratory tract viruses was 31.47%（677/2 151）. The positive rates were 1.39% for ADV,1.07% for IVA,1.16% for IVB,0.51% for PIV1,0.33% for PIV2,3.63% for PIV3 and 26.96% for RSV. There was statistical significance for the positive rates with different seasons（χ²=81.52,P<0.001）. The infection tended to occur in winter. RSV was the most common virus,and its positive rate was 38.64% in winter. There was statistical significance for the positive rates with different ages（χ²=18.30,P<0.001）. Infants of 28 d-<1 year old were more likely to be infected with the viruses,particularly RSV（27.72%）. The high proportions of mixed viral infection were 16.94%（21 cases） for RSV+IVB and 14.52%（18 cases） for RSV+ADV. RSV had the highest proportion of mixed viral infection with the other viruses（58.06%）. Mixed viral infection tended to occur in winter and among infants.Conclusions RSV is a main acute respiratory tract virus among children in Suzhou,especially among infants and in winter. For mixed viral infection,RSV is the most common virus.

Key words: Respiratory tract virus, Respiratory syncytial virus, Children