Analysis on the results of calcium and 25-hydroxy vitamin D of children in Panyu, Guangzhou

doi:10.3969/j.issn.1673-8640.2015.07.007

Abstract

Abstract: Objective

To analyze statistically the levels of calcium and 25-hydroxy vitamin D[25(OH)D] of children in Panyu, Guangzhou, in order to provide reference for child health care.

Methods

The levels of calcium and 25(OH)D were determined by atomic absorption spectrometer and electrochemiluminescence immunoassay from 1 902 children. The children were classified into 5 groups according to age, infancy group(1-12 months, 817 cases), toddler age group(1-2 years, 599 cases), preschool age group(3-6 years, 291 cases), school age group(7-11 years,167 cases) and adolescence group(12-18 years, 28 cases). Based on different age groups, each group was subclassified by male and female. The calcium and 25(OH)D levels were analyzed statistically.

Results

The average level of calcium was (1.72±0.19) mmol/L, and the average level of 25(OH)D was (39.12±11.26) ng/mL, and the levels of calcium and 25(OH)D had downward trend with the increasing of age. The levels of calcium and 25(OH)D in infancy group were higher than those in the other 4 groups(P<0.05). The levels of calcium in toddler age group was higher than those in preschool age group and school age group (P<0.05). The levels of 25(OH)D in toddler age group was higher than those in preschool age group, school age group and adolescence group. The levels of calcium and 25(OH)D in preschool age group were higher than those in school age group(P<0.05). There was no statistical significance for calcium and 25(OH)D levels with different sex (P>0.05). Calcium and 25(OH)D were in positive correlation [correlation coefficient (r)=0.221,P<0.05]. Linear equation was Y_calcium=0.004X_25(OH)D+1.573.

Conclusions

The levels of calcium and 25(OH)D are not high among Panyu children. The related schools and parents should supervise their children with calcium supplement rationly.

Key words: Calcium, 25-hydroxy vitamin D, Child, Atomic absorption spectrometer, Electrochemiluminescence immunoassay

CLC Number:

R446.1

XIAO Xing, HE Jinhua, LI Yuguang, HAN Zeping, HU Shufen, HUANG Hui. Analysis on the results of calcium and 25-hydroxy vitamin D of children in Panyu, Guangzhou[J]. Laboratory Medicine, 2015, 30(7): 694-696.

Figures/Tables 2

References 12

[1]	考验,施卫星,陈枢青.环境污染物质对儿童身高发育迟缓的影响[J].国际儿科学杂志,2009,36(5):491-493.
[2]	胡亚美,江载芳.实用儿科学[M].北京:人民卫生出版社,2002:3-5.
[3]	王夔. 生命科学中的微量元素分析与数据手册[M].北京:中国计量出版社,2003:308-311.
[4]	赵安琪. 从生理说起:钙与VD[J].中国药店,2013,14(12):53-54.
[5]	肖钘,何金花,黎毓光,等.广州市番禺区儿童全血5种微量元素检测结果分析[J].检验医学,2013,28(9):801-804.
[6]	吕葛,宋文琪,徐樨巍.北京地区儿童末梢血5种微量元素检测结果分析[J].中华检验医学杂志,2011,34(11):975-978.
[7]	査锡良. 生物化学[M].7版.北京:人民卫生出版社,2010:435-436.
[8]	刘晓敏,朱冰,郭敏,等.广州市11 524例儿童25羟基维生素D水平分析[J].国际检验医学杂志,2014,36(9):1226-1227.
[9]	郑明慧. 25(OH)D与总钙的研究进展[C].大连:第五届全国佝偻病防治学术会议,2002.
[10]	梁晓红,杨斌让,曾淑萍,等.0~2岁儿童VD营养水平及相关因素分析[J].中国初级卫生保健,2004,18(7):74-75.
[11]	陈名道. 补充维生素D:D3优于D2[J].中华内分泌代谢杂志,2013,29(10):912.
[12]	王园园,周连,陈晓东.灰霾对人体健康影响研究进展[J].江苏预防医学,2012,23(4):37-39.

组别	例数	总钙(mmol/L)	25(OH)D(ng/mL)
婴儿期组	817	1.79±0.18^△*#▲	42.99±10.13^△*#▲
男	443	1.79±0.18	42.84±10.17
女	374	1.79±0.18	43.17±10.10
幼儿期组	599	1.71±0.17^*#	41.29±10.17^*#▲
男	362	1.71±0.17	41.76±10.51
女	237	1.70±0.17	40.59±9.59
学龄前组	291	1.63±0.18^#	31.86±9.11^#
男	177	1.63±0.18	31.79±8.63
女	114	1.62±0.17	31.98±9.86
学龄期组	167	1.57±0.15	27.11±7.60
男	110	1.56±0.16	26.48±7.62
女	57	1.59±0.14	28.34±7.49
青春发育期组	28	1.64±0.19	26.49±10.16
男	18	1.64±0.18	26.53±10.92
女	10	1.66±0.21	26.43±9.18
合计	1 902	1.72±0.19	39.12±11.26
男	1 110	1.72±0.19	38.84±11.46
女	792	1.72±0.19	39.50±10.97

组别	例数	总钙(mmol/L)	25(OH)D(ng/mL)
婴儿期组	817	1.79±0.18^△*#▲	42.99±10.13^△*#▲
男	443	1.79±0.18	42.84±10.17
女	374	1.79±0.18	43.17±10.10
幼儿期组	599	1.71±0.17^*#	41.29±10.17^*#▲
男	362	1.71±0.17	41.76±10.51
女	237	1.70±0.17	40.59±9.59
学龄前组	291	1.63±0.18^#	31.86±9.11^#
男	177	1.63±0.18	31.79±8.63
女	114	1.62±0.17	31.98±9.86
学龄期组	167	1.57±0.15	27.11±7.60
男	110	1.56±0.16	26.48±7.62
女	57	1.59±0.14	28.34±7.49
青春发育期组	28	1.64±0.19	26.49±10.16
男	18	1.64±0.18	26.53±10.92
女	10	1.66±0.21	26.43±9.18
合计	1 902	1.72±0.19	39.12±11.26
男	1 110	1.72±0.19	38.84±11.46
女	792	1.72±0.19	39.50±10.97

[1]	WANG Huiying, TANG Yu, DONG Lili, WANG Jing. Role of Mycoplasma pneumoniae RNA determination in diagnosis and efficacy monitoring of pneumonia in children [J]. Laboratory Medicine, 2023, 38(9): 865-869.
[2]	SHI Yingying, PAN Fen, SUN Yan, WANG Chun, JIANG Jie, YU Fangyuan, ZHANG Tiandong, QIN Huihong, ZHANG Hong. Nested multiple polymerase chain reaction in rapid diagnosis of meningitis/encephalitis in children [J]. Laboratory Medicine, 2023, 38(8): 766-770.
[3]	FU Limei, YANG Dan, XU Jin, ZHU Haiyan, ZHU Fenhua. Clinical significance of whole blood trace elements and serum vitamin levels in 6 common skin diseases in children [J]. Laboratory Medicine, 2023, 38(8): 771-775.
[4]	ZHANG Xin, MA Lijuan. Role of cardiac markers in children [J]. Laboratory Medicine, 2023, 38(6): 505-509.
[5]	YANG Qiong, XU Fen, LIN Yahui. Clinical application of cardiac troponin determination in pediatric cardiac involvement related diseases [J]. Laboratory Medicine, 2023, 38(6): 510-517.
[6]	LI Li, SUN Haiyan, LI Yuanrui, DOU Min, TANG Wen, JIANG Limin, SHEN Lisong. Changes and clinical roles of perioperative NT-proBNP and PCT in children with congenital heart disease [J]. Laboratory Medicine, 2023, 38(6): 524-531.
[7]	WANG Yaling, HUANG Yunli, TIAN Mi, WANG Shunlan, XIAO Li. Relationship between EOS%，CCR3，eotaxin and disease severity in children with acute bronchopneumonia [J]. Laboratory Medicine, 2023, 38(3): 230-234.
[8]	WU Jinying, FANG Yulian, WANG Wei, HOU Mengzhu, WANG Lu, ZHAO Yu. Clinical characteristics and epidemiological of enterovirus infection in children with acute diarrhea in Tianjin [J]. Laboratory Medicine, 2023, 38(3): 267-271.
[9]	ZHAO Yanhong, FU Lin, LIU Biao, XIAO Meifang. Reference interval of lactate dehydrogenase among 3-14-year-old population in Hainan [J]. Laboratory Medicine, 2023, 38(11): 1041-1043.
[10]	HU Shaohua, CHEN Li, ZHAO Meng, MA Zhan, ZHANG Hong. Epidemiological characteristic analysis of Mycoplasma pneumoniae infection in children in Shanghai [J]. Laboratory Medicine, 2023, 38(1): 14-17.
[11]	WEI Rui, YUAN Xu, TIAN Xuewen, LU Yanjun. Clinical and laboratory characteristics of human metapneumovirus infection children in a Grade A Class 3 hospital in Wuhan [J]. Laboratory Medicine, 2023, 38(1): 18-22.
[12]	LU Lijuan, XU Jin. Thoughts on whether adenovirus is the cause of the hepatitis of unknown etiology among children recently [J]. Laboratory Medicine, 2022, 37(8): 705-709.
[13]	AO Jiajia, ZHANG Junfeng, NIE Wenjian, YE Qing. Relationship of fasting C-peptide with nonalcoholic fatty liver disease in children with obesity [J]. Laboratory Medicine, 2022, 37(7): 618-622.
[14]	PAN Fen, PAN Yuxuan, SHI Yingying, YU Fangyuan, ZHANG Hong. UroQuick rapid urine culture technique for urinary tract infection in children [J]. Laboratory Medicine, 2022, 37(7): 652-656.
[15]	HUANG Liying, SAI Fangfang, ZHANG Kebei, MENG Chao. Correlation between admission blood calcium level and the prognosis of patients with hypertensive intracerebral hemorrhage [J]. Laboratory Medicine, 2022, 37(5): 423-428.