The research progress of early warning biomarker for sepsis

doi:10.3969/j.issn.1673-8640.2015.05.029

Abstract

Abstract:

Sepsis is a kind of systemic inflammatory response syndromes(SIRS) induced by infection, which has been clinically confirmed the presence of bacteria or highly suspicious infections. More and more researchers have paid attention to the early diagnosis of sepsis recently. This review has focused on the capabilities of cytokine, procalcitonin(PCT), endotoxin, high-sensitivity C reactive protein(hs-CRP), serum amyloid protein A(SAA), heparin-binding protein(HBP), (1,3)-beta-D-glucan(BG) and galactomannan(GM) to diagnose sepsis early and assess the severity and prognosis, in order to provide new thoughts for the early diagnosis and treatment of sepsis.

Key words: Sepsis, Cytokine, Procalcitonin, Endotoxin, High-sensitivity C reactive protein, Serum amyloid protein A, Heparin-binding protein, (1,3)-beta-D-glucan, Galactomannan

CLC Number:

R446.5

XU Cheng, XU Yuanhong. The research progress of early warning biomarker for sepsis[J]. Laboratory Medicine, 2015, 30(5): 533-536.

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