Abstract:

Objective To analyze the antibiotic resistance and characteristic of Klebsiella pneumoniae isolated from neurosurgical intensive care unit in Huashan Hospital. Methods A total of 233 Klebsiella pneumoniae isolates were collected from neurosurgical intensive care unit. Antibiotic susceptibility of the isolates was determined. Results A total of 77.3% of 233 isolates of Klebsiella pneumoniae were collected from respiratory tract samples. The total resistance rates to antibiotics increased year after year. The resistance rates to piperacillin-tazobactam, cefoperazone-sulbactam, imipenem, meropenem and ertapenem for respiratory tract samples were obviously lower than those for non-respiratory tract samples (P<0.05). Conclusions There is a contrast between the antibiotic susceptibility of the respitatory specimens and the non respiratory specimens. The monitoring of nosocomial infection should be strengthened to avoid misusing antibiotics.

Key words: Klebsiella pneumoniae, Respiratory tract sample, Colonization bacterium, Nosocomial infection