Laboratory Medicine ›› 2018, Vol. 33 ›› Issue (9): 839-843.DOI: 10.3969/j.issn.1673-8640.2018.09.016

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Research progress in the virulence factors of Klebsiella pneumoniae liver abscess

GUAN Hongyan, LIU Ying   

  1. Department of Clinical Laboratory,Xinhua Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200092,China
  • Received:2017-12-01 Online:2018-09-30 Published:2018-10-13

Abstract:

Liver abscess is a pyogenic infection of the liver which is usually caused by amoeba histolytica or bacteria. It is a common digestive system disease and has a high fatality rate. Nowadays,Klebsiella pneumoniae has emerged as the main pathogen of bacterial liver abscess. Virulence factors,which contribute to the pathogenicity of Klebsiella pneumoniae, are identified,such as capsular polysaccharides,lipopolysaccharides,iron uptake system and fimbriae. Klebsiella pneumoniae liver abscess(KLA) is usually caused by hypervirulent strains. Here,the main virulence factors of KLA are summarized.

Key words: Klebsiella pneumoniae, Liver abscess, Virulence factor

CLC Number: