Challenge on the clinical examination for gravidas and children

doi:10.3969/j.issn.1673-8640.2014.11.001

Abstract

Abstract:

With the rapid development in medicine and related fields, advanced determination technologies and novel clinical indicators are emerging rapidly. As for the distinct characteristics of gravidas and children, the demands for clinical indicators and determination technologies are different from those in adults. There will be an important challenge on the clinical examination for gravidas and children, such as normal reference interval establishment and the standardization and clinical rational explanation for novel clinical indicators and advanced determination technologies.

Key words: Gravida, Child, Clinical examination, Challenge

CLC Number:

R446.1

FU Qihua, YANG Haiou.. Challenge on the clinical examination for gravidas and children[J]. , 2014, 29(11): 1081-1083.

References

[1] Carraro P,Plebani M. Errors in a stat laboratory:types and frequencies 10 years later[J]. Clin Chem,2007,53(7):1338-1342.
[2] 中华人民共和国卫生部通告卫通〔2012〕23号[S]. 中华人民共和国卫生部,2012.
[3] Bailey D,Colantonio D,Kyriakopoulou L,et al.Marked biological variance in endocrine and biochemical markers in childhood: establishment of pediatric reference intervals using healthy community children from the CALIPER cohort[J]. Clin Chem,2013,59(9):1393-1405.
[4] Colantonio DA,Kyriakopoulou L,Chan MK,et al.Closing the gaps in pediatric laboratory reference intervals: a CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children[J].Clin Chem,2012,58(5):854-868.
[5] Konforte D,Shea JL,Kyriakopoulou L,et al.Complex biological pattern of fertility hormones in children and adolescents: a study of healthy children from the CALIPER cohort and establishment of pediatric reference intervals[J].Clin Chem,2013,59(8):1215-1227.
[6] Estey MP,Cohen AH,Colantonio DA,et al.CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman,Ortho,Roche and Siemens Clinical Chemistry Assays: direct validation using reference samples from the CALIPER cohort[J].Clin Biochem,2013,46(13-14): 1197-1219.
[7] Zheng Z, Geng J, Yao RE,et al. Molecular defects identified by whole exome sequencing in a child with Fanconi anemia[J]. Gene, 2013,530(2):295-300.
[8] Wagenstaller J,Spranger S,Lorenz-Depiereux B,et al. Copy-number variations measured by single-nucleotide-polymorphism oligonucleotide arrays in patients with mental retardation[J]. Am J Hum Genet,2007,81(4): 768-779.
[9] Saikumar J,Ramachandran K,Vaidya VS. Non-invasive micromarkers[J].Clin Chem,2014,60(9): 1158-1173.
[10] Sandoval J,Peiró-Chova L,Pallardó FV,et al.Epigenetic biomarkers in laboratory diagnostics: emerging approaches and opportunities[J]. Expert Rev Mol Diagn,2013,13(5):457-471.
[11] Chrystoja CC,Diamandis EP.Whole genome sequencing as a diagnostic test: challenges and opportunities[J].Clin Chem,2014,60(5):724-733.

[1]	WANG Huiying, TANG Yu, DONG Lili, WANG Jing. Role of Mycoplasma pneumoniae RNA determination in diagnosis and efficacy monitoring of pneumonia in children [J]. Laboratory Medicine, 2023, 38(9): 865-869.
[2]	SHI Yingying, PAN Fen, SUN Yan, WANG Chun, JIANG Jie, YU Fangyuan, ZHANG Tiandong, QIN Huihong, ZHANG Hong. Nested multiple polymerase chain reaction in rapid diagnosis of meningitis/encephalitis in children [J]. Laboratory Medicine, 2023, 38(8): 766-770.
[3]	FU Limei, YANG Dan, XU Jin, ZHU Haiyan, ZHU Fenhua. Clinical significance of whole blood trace elements and serum vitamin levels in 6 common skin diseases in children [J]. Laboratory Medicine, 2023, 38(8): 771-775.
[4]	ZHANG Xin, MA Lijuan. Role of cardiac markers in children [J]. Laboratory Medicine, 2023, 38(6): 505-509.
[5]	YANG Qiong, XU Fen, LIN Yahui. Clinical application of cardiac troponin determination in pediatric cardiac involvement related diseases [J]. Laboratory Medicine, 2023, 38(6): 510-517.
[6]	LI Li, SUN Haiyan, LI Yuanrui, DOU Min, TANG Wen, JIANG Limin, SHEN Lisong. Changes and clinical roles of perioperative NT-proBNP and PCT in children with congenital heart disease [J]. Laboratory Medicine, 2023, 38(6): 524-531.
[7]	WANG Yaling, HUANG Yunli, TIAN Mi, WANG Shunlan, XIAO Li. Relationship between EOS%，CCR3，eotaxin and disease severity in children with acute bronchopneumonia [J]. Laboratory Medicine, 2023, 38(3): 230-234.
[8]	WU Jinying, FANG Yulian, WANG Wei, HOU Mengzhu, WANG Lu, ZHAO Yu. Clinical characteristics and epidemiological of enterovirus infection in children with acute diarrhea in Tianjin [J]. Laboratory Medicine, 2023, 38(3): 267-271.
[9]	ZHAO Yanhong, FU Lin, LIU Biao, XIAO Meifang. Reference interval of lactate dehydrogenase among 3-14-year-old population in Hainan [J]. Laboratory Medicine, 2023, 38(11): 1041-1043.
[10]	HU Shaohua, CHEN Li, ZHAO Meng, MA Zhan, ZHANG Hong. Epidemiological characteristic analysis of Mycoplasma pneumoniae infection in children in Shanghai [J]. Laboratory Medicine, 2023, 38(1): 14-17.
[11]	WEI Rui, YUAN Xu, TIAN Xuewen, LU Yanjun. Clinical and laboratory characteristics of human metapneumovirus infection children in a Grade A Class 3 hospital in Wuhan [J]. Laboratory Medicine, 2023, 38(1): 18-22.
[12]	LU Lijuan, XU Jin. Thoughts on whether adenovirus is the cause of the hepatitis of unknown etiology among children recently [J]. Laboratory Medicine, 2022, 37(8): 705-709.
[13]	AO Jiajia, ZHANG Junfeng, NIE Wenjian, YE Qing. Relationship of fasting C-peptide with nonalcoholic fatty liver disease in children with obesity [J]. Laboratory Medicine, 2022, 37(7): 618-622.
[14]	PAN Fen, PAN Yuxuan, SHI Yingying, YU Fangyuan, ZHANG Hong. UroQuick rapid urine culture technique for urinary tract infection in children [J]. Laboratory Medicine, 2022, 37(7): 652-656.
[15]	ZHAO Ying, XU Jin. Role of fecal calprotectin in children's intestinal diseases [J]. Laboratory Medicine, 2022, 37(5): 429-432.