›› 2014, Vol. 29 ›› Issue (5): 564-569.DOI: 10.3969/j.issn.1673-8640.2014.05.030

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Calcium sensing receptor and regulation of related signal transduction pathways on the secretion of cytokine

WU Qiuyue, SUN Yihua.   

  1. Department of Clinical Laboratory, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Harbin 150081, China
  • Received:2013-08-09 Online:2014-05-30 Published:2014-05-27

Abstract: In this article, we summary the calcium sensing receptor(CaSR) structure, signal transduction and physiological function. The regulation mechanism of CaSR on the secretion of cytokines was described through the related signal transduction pathways, and we prospect the relations between them.

Key words: Calcium sensing receptor, Cytokine, Nuclear transcription factor-kappa B pathway, Mitogen activated protein kinase pathway

CLC Number: