检验医学 ›› 2024, Vol. 39 ›› Issue (9): 865-870.DOI: 10.3969/j.issn.1673-8640.2024.09.008

• 论著 • 上一篇    下一篇

北京某三甲医院2012—2023年健康体检人群空腹血糖变化趋势分析

李孟涵1, 贺晓菲2, 张琼3, 周玉1()   

  1. 1.中国人民解放军总医院第二医学中心检验科 国家老年疾病临床研究中心,北京 100853
    2.鄂尔多斯市中心医院检验科,内蒙古 鄂尔多斯 010700
    3.中国人民解放军总医院第六医学中心检验科,北京 100048
  • 收稿日期:2023-09-26 修回日期:2024-06-16 出版日期:2024-09-30 发布日期:2024-10-15
  • 通讯作者: 周 玉,E-mail:zhouy427@163.com
  • 作者简介:李孟涵,女,1996年生,学士,技师,主要从事临床生化检验工作。

Change trend of fasting plasma glucose of healthy subjects in a Grade 3A hospital in Beijing from 2012 to 2023

LI Menghan1, HE Xiaofei2, ZHANG Qiong3, ZHOU Yu1()   

  1. 1. Department of Clinical Laboratory,the Second Medical Center of Chinese People's Liberation Army General Hospital,the National Clinical Research Center for Geriatric Diseases,Beijing 100853,China
    2. Department of Clinical Laboratory,Ordos Central Hospital,Ordos 010700,Inner Mongolia,China
    3. Department of Clinical Laboratory,the Sixth Medical Center of Chinese People's Liberation Army General Hospital,Beijing 100048,China
  • Received:2023-09-26 Revised:2024-06-16 Online:2024-09-30 Published:2024-10-15

摘要:

目的 分析2012—2023年北京某三甲医院健康体检人群空腹血糖(FPG)的变化趋势。方法 收集2012—2023年中国人民解放军总医院第二医学中心33 600名健康体检者的FPG检测结果。以FPG≥6.1 mmol·L-1为异常。按年龄(18~30岁、31~40岁、41~50岁和51~60岁)和性别分别分组。采用线性回归分析评估FPG与年份之间的关系,采用趋势X2检验分析FPG异常率与年份之间的关系。结果 2012—2023年,18~30岁组、31~40岁组、51~60岁组FPG水平和异常率均与年份呈线性关系(P<0.05),随年份呈上升趋势。除2022年和2023年18~30岁组FPG水平和异常率稍高于31~40岁组(P>0.05)外,其他年份各年龄组之间FPG水平和异常率差异均有统计学意义(P<0.05),且随年龄的增高,FPG水平和异常率均逐渐升高。相对于2012年,2023年各年龄组FPG异常人数和异常率增长情况为51~60岁组>18~30岁组>31~40岁组>41~50岁组。各年龄组男性FPG水平和异常率均高于同年龄组女性(P<0.01),且男性、女性FPG水平和异常率均随年龄的增加而升高。结论 2012—2023年中国人民解放军总医院第二医学中心健康体检人群FPG水平和异常率均呈上升趋势,且男性高于女性,呈现年轻化趋势。

关键词: 空腹血糖, 异常率, 年龄, 性别, 年轻化, 健康人群

Abstract:

Objective To investigate the change trend of fasting plasma glucose (FPG) of healthy subjects in a Grade 3A hospital in Beijing from 2012 to 2023. Methods The FPG determination results were collected from 33 600 healthy subjects in the Second Medical Center of Chinese People's Liberation Army General Hospital from 2012 to 2023. FPG≥6.1 mmol·L-1 was abnormal. They were classified by ages (18-30 years old group,31-40 years old group,41-50 years old group and 51-60 years old group) and genders. Linear regression analysis was used to evaluate the relationship between FPG and years,and trend X2 test was used to analyze the relationship between FPG abnormal rate and years. Results From 2012 to 2023,the FPG level and abnormal rate in 18-30 years old group,31-40 years old group and 51-60 years old group were linearly correlated with years (P<0.05),which showed an increasing trend with the increase of years. The FPG level and abnormal rate in 18-30 years old group were slightly higher than those in 31-40 years old group in 2022 and 2023 (P>0.05),and there was statistical significance in FPG level and abnormal rate among all the age groups in the other years (P<0.05),and the FPG level and abnormal rate gradually increased with the increase of ages. Compared with 2012,the increase of FPG abnormal number and abnormal rate in the 4 age groups in 2023 was successively 51-60 years old,>18-30 years old,>31-40 years old and >41-50 years old. The FPG level and abnormal rate of males in all the age groups were higher than that of females(P<0.01),and the FPG level and abnormal rate of males and females were increased with the increase of ages. Conclusions From 2012 to 2023,in the Second Medical Center of Chinese People's Liberation Army General Hospital the FPG level and abnormal rate of healthy subjects show an increasing trend,and that of male is higher than that of female,showing a younger trend.

Key words: Fasting plasma glucose, Abnormal rate, Age, Gender, Younger, Healthy subject

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