妇儿检验所面临的挑战

doi:10.3969/j.issn.1673-8640.2014.11.001

检验医学 ›› 2014, Vol. 29 ›› Issue (11): 1081-1083.DOI: 10.3969/j.issn.1673-8640.2014.11.001

• 妇儿检验专题 • 下一篇

妇儿检验所面临的挑战

傅启华，杨海鸥

上海交通大学医学院附属上海儿童医学中心检验科,上海 200127

收稿日期:2014-09-01 出版日期:2014-11-01 发布日期:2014-11-28
作者简介:傅启华，男，1967年生，博士，主任技师，博士生导师，主要从事遗传性疾病分子诊断工作。

Challenge on the clinical examination for gravidas and children

FU Qihua, YANG Haiou.

Department of Clinical Laboratory, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China

Received:2014-09-01 Online:2014-11-01 Published:2014-11-28

摘要/Abstract

摘要：

随着医学及相关学科领域的飞速发展,新的检测技术和检测指标不断涌现。孕产妇和儿童作为特殊的群体,在检验项目、检测方法等方面的要求与一般成人存在差异。孕产妇与儿童检验项目正常参考区间的建立、新的检测指标和检测技术应用于临床的标准化、规范化及临床合理解释等问题,将是妇儿检验未来所面临的重要挑战之一。

关键词: 孕产妇, 儿童, 检验, 挑战

Abstract:

With the rapid development in medicine and related fields, advanced determination technologies and novel clinical indicators are emerging rapidly. As for the distinct characteristics of gravidas and children, the demands for clinical indicators and determination technologies are different from those in adults. There will be an important challenge on the clinical examination for gravidas and children, such as normal reference interval establishment and the standardization and clinical rational explanation for novel clinical indicators and advanced determination technologies.

Key words: Gravida, Child, Clinical examination, Challenge

中图分类号:

R446.1

傅启华，杨海鸥. 妇儿检验所面临的挑战[J]. 检验医学, 2014, 29(11): 1081-1083.

FU Qihua, YANG Haiou.. Challenge on the clinical examination for gravidas and children[J]. , 2014, 29(11): 1081-1083.

参考文献

[1] Carraro P,Plebani M. Errors in a stat laboratory:types and frequencies 10 years later[J]. Clin Chem,2007,53(7):1338-1342.
[2] 中华人民共和国卫生部通告卫通〔2012〕23号[S]. 中华人民共和国卫生部,2012.
[3] Bailey D,Colantonio D,Kyriakopoulou L,et al.Marked biological variance in endocrine and biochemical markers in childhood: establishment of pediatric reference intervals using healthy community children from the CALIPER cohort[J]. Clin Chem,2013,59(9):1393-1405.
[4] Colantonio DA,Kyriakopoulou L,Chan MK,et al.Closing the gaps in pediatric laboratory reference intervals: a CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children[J].Clin Chem,2012,58(5):854-868.
[5] Konforte D,Shea JL,Kyriakopoulou L,et al.Complex biological pattern of fertility hormones in children and adolescents: a study of healthy children from the CALIPER cohort and establishment of pediatric reference intervals[J].Clin Chem,2013,59(8):1215-1227.
[6] Estey MP,Cohen AH,Colantonio DA,et al.CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman,Ortho,Roche and Siemens Clinical Chemistry Assays: direct validation using reference samples from the CALIPER cohort[J].Clin Biochem,2013,46(13-14): 1197-1219.
[7] Zheng Z, Geng J, Yao RE,et al. Molecular defects identified by whole exome sequencing in a child with Fanconi anemia[J]. Gene, 2013,530(2):295-300.
[8] Wagenstaller J,Spranger S,Lorenz-Depiereux B,et al. Copy-number variations measured by single-nucleotide-polymorphism oligonucleotide arrays in patients with mental retardation[J]. Am J Hum Genet,2007,81(4): 768-779.
[9] Saikumar J,Ramachandran K,Vaidya VS. Non-invasive micromarkers[J].Clin Chem,2014,60(9): 1158-1173.
[10] Sandoval J,Peiró-Chova L,Pallardó FV,et al.Epigenetic biomarkers in laboratory diagnostics: emerging approaches and opportunities[J]. Expert Rev Mol Diagn,2013,13(5):457-471.
[11] Chrystoja CC,Diamandis EP.Whole genome sequencing as a diagnostic test: challenges and opportunities[J].Clin Chem,2014,60(5):724-733.

[1]	王慧英, 汤昱, 董利利, 王静. 肺炎支原体RNA检测用于肺炎患儿疾病诊断和疗效监测[J]. 检验医学, 2023, 38(9): 865-869.
[2]	赵若楠, 盛哲, 叶志成, 杨丹, 余先智. 上海某儿科医院新型冠状病毒肺炎疫情前后腹泻患儿A组轮状病毒流行特征[J]. 检验医学, 2023, 38(9): 890-892.
[3]	石迎迎, 潘芬, 孙燕, 王春, 蒋婕, 于方圆, 张天栋, 秦惠宏, 张泓. 巢式多重聚合酶链反应快速诊断儿童脑膜炎/脑炎[J]. 检验医学, 2023, 38(8): 766-770.
[4]	符利梅, 杨丹, 徐锦, 朱海燕, 朱芬华. 全血微量元素和血清维生素检测在6种儿童常见皮肤病中的临床意义[J]. 检验医学, 2023, 38(8): 771-775.
[5]	张欣, 马丽娟. 儿童心脏标志物检测的临床意义[J]. 检验医学, 2023, 38(6): 505-509.
[6]	杨琼, 徐芬, 蔺亚晖. 心肌肌钙蛋白检测在儿科心脏受累相关疾病中的临床应用[J]. 检验医学, 2023, 38(6): 510-517.
[7]	李莉, 孙海燕, 李媛睿, 窦敏, 汤文, 蒋黎敏, 沈立松. 先天性心脏病患儿围手术期NT-proBNP、 PCT变化及其临床意义[J]. 检验医学, 2023, 38(6): 524-531.
[8]	王雅玲, 黄运丽, 田密, 王顺兰, 肖莉. 急性支气管肺炎患儿EOS%、CCR3、Eotaxin与病情严重程度的关系[J]. 检验医学, 2023, 38(3): 230-234.
[9]	武晋英, 方玉莲, 王维, 侯梦珠, 王露, 赵煜. 天津地区急性腹泻患儿肠道病毒感染临床特征和流行病学分析[J]. 检验医学, 2023, 38(3): 267-271.
[10]	张嘉懿, 郭文伟, 沈永明, 娜仁, 崔小健, 司萍. 光激化学发光法检测儿童乙型肝炎核心抗体最佳临界值探讨[J]. 检验医学, 2023, 38(3): 291-293.
[11]	赵艳宏, 傅琳, 刘彪, 肖美芳. 海南地区3~14岁人群乳酸脱氢酶参考区间分析[J]. 检验医学, 2023, 38(11): 1041-1043.
[12]	徐黎明, 王瑾, 袁梦娇, 王金金. 患者数据指数加权移动平均法在区域检验中心MCV、MCH、MCHC项目稳定性和可比性监测中的应用[J]. 检验医学, 2023, 38(11): 1098-1100.
[13]	戴淑芝, 宋美燕, 米腊腊, 张敏, 马丽娟. 基于GAMLSS模型的北京地区儿童C反应蛋白百分位数分布曲线和参考值[J]. 检验医学, 2023, 38(10): 977-979.
[14]	胡韶华, 陈黎, 赵梦, 马展, 张泓. 上海地区儿童肺炎支原体感染流行病学特征分析[J]. 检验医学, 2023, 38(1): 14-17.
[15]	魏瑞, 袁旭, 田学文, 鲁艳军. 武汉市某三级甲等医院人偏肺病毒感染患儿实验室检测结果和临床特征分析[J]. 检验医学, 2023, 38(1): 18-22.

妇儿检验所面临的挑战

Challenge on the clinical examination for gravidas and children

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics