检验医学 ›› 2014, Vol. 29 ›› Issue (1): 1-3.DOI: 10.3969/j.issn.1673-8640.2014.01.001

• 乙型肝炎病毒感染者细胞免疫的临床监测专题 •    下一篇

重视乙型肝炎病毒感染者细胞免疫的临床研究

朱晴晖   

  1. 上海市普陀区人民医院(纺一医院)中心实验室, 上海 200060
  • 收稿日期:2013-12-16 出版日期:2014-01-20 发布日期:2014-01-20
  • 作者简介:朱晴晖, 女, 1947年生, 主任技师, 主要从事免疫学和分子生物学的实验及应用研究。

Pay closer attention to the clinical research for cellular immunity of subjects infected with hepatitis B virus

ZHU Qinghui   

  1. Center for Experiment, Shanghai People′s Hospital of Putuo District (Shanghai First Textile Hospital), Shanghai 200060, China
  • Received:2013-12-16 Online:2014-01-20 Published:2014-01-20

摘要:

乙型肝炎病毒(HBV)感染者的细胞免疫功能是其识别并清除病毒(急性自限性感染)抑或表现为免疫耐受(慢性持续感染)的关键因素, 与疾病的预后和转归密切相关, 从而决定了HBV感染者细胞免疫的临床监测的必要性。本文评价了“乙型肝炎病毒感染者细胞免疫的临床监测”专题刊登的综述和论文的特点。基础免疫学研究的发展将给临床免疫学研究提供更广的领域。期待临床和实验室对HBV感染者细胞免疫临床研究的重视。

关键词: 乙型肝炎病毒, 慢性感染, 细胞免疫

Abstract:

The cellular immunity of subjects infected with hepatitis B virus(HBV) is the critical factor for their recognizing and clearing virus (acute self limiting infection) or showing immune tolerance (chronic persistent infection), and is tightly correlated with the disease prognosis and outcome. Thus, the clinical monitoring cellular immunity of subjects infected with HBV is very necessary. The characteristics of the review and papers published in the special subject, Clinical Monitoring for the Cellular Immunity of Subjects Infected with Hepatitis B Virus, are evaluated. The development of studies in basic immunology will provide wider field for studies in clinical immunology. The closer attention of physicians and experimenters to the clinical research for cellular immunity of subjects infected with HBV is being expected.

Key words: Hepatitis B virus, Chronic infection, Cellular immunity

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