整合子与细菌耐药相关性研究进展

doi:10.3969/j.issn.1673-8640.2016.04.017

摘要/Abstract

摘要：

整合子是近年来被发现的一种新的遗传结构元件,能够识别外界的耐药基因,可以通过位点特异性重组的方式捕获耐药基因并使其表达;也可以位于质粒或转座子上,作为质粒或转座子的一个组成部分,在转移的过程中使耐药基因在细菌中发生播散。整合子因为与细菌耐药性的产生和传播关系密切而备受各方的关注。

关键词: 整合子, 耐药基因, 传播

Abstract:

Integron is a mobile gene element being found recently. It could recognize drug resistance gene from outside. It can also recombine exogenous gene and express by site-specific recombination. In addition,integron is located at transposon or plasmid,and by being a part of it transmitting drug resistance gene. Researches on integron are attracting many interests for its importance in the generation of drug resistance and transmission.

Key words: Integron, Drug resistance gene, Transmission

中图分类号:

R446.5

李情操, 魏取好, 卢雯君, 赵玉杰. 整合子与细菌耐药相关性研究进展[J]. 检验医学, 2016, 31(4): 324-328.

LI Qingcao, WEI Quhao, LU Wenjun, ZHAO Yujie. Progress on the correlation between integrons and bacterial drug resistance[J]. Laboratory Medicine, 2016, 31(4): 324-328.

图/表 1

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