| [1] 范倩燕,沈 敏,汤园园,等. 医院感染的病原菌特点及耐药性分析[J].检验医学,2012,27(5):396-399.[2] D′Costa VM, King CE, Kalan L, et al. Antibiotic resistance is ancient[J]. Nature, 2011, 477(7365): 457-461.[3] Gupta AK, Reddy VP, Lavania M, et al. jefA (Rv2459), a drug efflux gene in Mycobacterium tuberculosis confers resistance to isoniazid & ethambutol [J]. Indian J Med Res, 2010, 132: 176-188.[4] He GX, Thorpe C, Walsh D, et al. EmmdR, a new member of the MATE family of multidrug trans-porters, extrudes quinolones from Enterobacter cloacae[J]. Arch Microbiol, 2011, 193(10): 759-765.[5] Ruiz C, Levy SB. Many chromosomal genes modulate MarA-mediated multidrug resistance in Escherichia coli[J]. Antimicrob Agents Chemother, 2010, 54(5): 2125-2134.[6] Karczmarczyk M, Martins M, Quinn T, et al. Mechanisms of fluoroquinolone resistance in Escherichia coli isolates from food-producing animals[J]. Appl Environ Microbiol, 2011, 77(20): 7113-7120.[7] Li XZ, Nikaido H. Efflux-mediated drug resistance in bacteria: an update[J]. Drugs, 2009, 69(12): 1555-1623.[8] Delgado MA, Vincent PA, Farías RN, et al. YojI of Escherichia coli functions as a microcin J25 efflux pump[J]. J Bacteriol,2005, 187(10): 3465-3470.[9] Socías SB, Vincent PA, Salomón RA. The leucine-responsive regulatory protein, Lrp, modulates microcin J25 intrinsic resistance in Escherichia coli by regulating expression of the YojI microcin exporter[J]. J Bacteriol, 2009, 191(4): 1343-1348.[10] Al-Hamad A, Upton M, Burnie J. Molecular cloning and characterization of SmrA, a novel ABC multidrug efflux pump from Stenotrophomonas maltophilia[J]. J Antimicrob Chemother, 2009, 64(4): 731-734.[11] Srinivasan VB, Rajamohan G, Gebreyes WA. Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii[J]. Antimicrob Agents Chemother, 2009, 53(12): 5312-5316.[12] Liu J, Keelan P, Bennett PM, et al. Characterization of a novel macrolide efflux gene, mef(B), found linked to sul3 in porcine Escherichia coli[J]. J Antimicrob Chemother, 2009, 63(3): 423-426.[13] Cattoir V, Poirel L, Nordmann P. Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France[J]. Antimicrob Agents Chemother, 2008, 52(10): 3801-3804.[14] Baudry PJ, Nichol K, DeCorby M, et al. Mechanisms of resistance and mobility among multidrug-resistant CTX-M-producing Escherichia coli from Canadian intensive care units: the 1st report of QepA in North America[J]. Diagn Microbiol Infect Dis, 2009, 63(3): 319-326.[15] Rajamohan G, Srinivasan VB, Gebreyes WA. Mole-cular and functional characterization of a novel efflux pump, AmvA, mediating antimicrobial and dis-infectant resistance in Acinetobacter baumannii[J]. J Antimicrob Chemother, 2010, 65(9): 1919-1925.[16] Smith KP, Kumar S, Varela MF. Identification, cloning, and functional characterization of EmrD-3, a putative multidrug efflux pump of the major facilitator superfamily from Vibrio cholerae O395[J]. Arch Microbiol, 2009, 191(12): 903-911.[17] Yin Y, He X, Szewczyk P, et al. Structure of the multidrug transporter EmrD from Escherichia coli[J]. Science, 2006, 312(5774): 741-744.[18] Kuroda T, Tsuchiya T. Multidrug efflux transporters in the MATE family[J]. Biochim Biophys Acta, 2009, 1794(5): 763-768.[19] Matsumoto T, Kanamoto T, Otsuka M, et al. Role of glutamate residues in substrate recognition by human MATE1 polyspecific H+/organic cation exporter[J]. Am J Physiol Cell Physiol, 2008, 294 (4): C1074-C1078.[20] Schulz R, Kleinekathfer U. Transitions between closed and open conformations of TolC: the effects of ions in simulations[J]. Biophys J, 2009, 96(8): 3116-3125.[21] Pos KM. Trinity revealed: stoichiometric complex assembly of a bacterial multidrug efflux pump[J]. Proc Natl Acad Sci USA, 2009, 106(17): 6893-6894.[22] Symmons MF, Bokma E, Koronakis E, et al. The assembled structure of a complete tripartite bacterial multidrug efflux pump[J]. Proc Natl Acad Sci USA, 2009, 106(17): 7173-7178.[23] Tikhonova EB, Yamada Y, Zgurskaya HI. Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC[J]. Chem Biol, 2011, 18(4): 454-463.[24] Eicher T, Brandsttter L, Pos KM. Structural and functional aspects of the multidrug efflux pump AcrB[J]. Biol Chem, 2009, 390(8): 693-699.[25] Lim SP, Nikaido H. Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli[J]. Antimicrob Agents Chemother, 2010, 54(5): 1800-1806.[26] Deininger KN, Horikawa A, Kitko RD, et al. A requirement of TolC and MDR efflux pumps for acid adaptation and GadAB induction in Escherichia coli[J]. PLoS One, 2011, 6(4): e18960.[27] Husain F, Nikaido H. Substrate path in the AcrB multidrug efflux pump of Escherichia coli[J]. Mol Microbiol, 2010, 78(2): 320-330. |
