Influence of military stress on immune function among recruits

doi:10.3969/j.issn.1673-8640.2016.03.009

Abstract

Abstract:

Objective To investigate the changes of cellular immunity and humoral immunity among recruits before and after military training. Methods A total of 60 recruits participated military training in enlisted military training base, and the symptom checklists（SCL-90） were used to scale their psychological symptoms before and after military training, respectively. Their serum immunoglobulin and complement function were determined, and natural killer（NK） cell, B lymphocyte, CD4⁺ T lymphocyte, CD8⁺ T lymphocyte, interleukin 2（IL-2） and interleukin 10（IL-10） levels were determined. Results The SCL-90 total score,somatization, depression and paranoia score after military training increased significantly than those before military training（P<0.05）. The levels of serum IgG, IgA and IgM, B lymphocyte, NK cell ,peripheral blood CD4⁺ T lymphocyte, CD8⁺ T lymphocyte and CD4⁺/CD8⁺ ratio decreased significantly （P<0.05 or P<0.01）. The level of peripheral blood IL-2 decreased after military training（P<0.05）, and the level of peripheral blood IL-10 increased significantly （P<0.05）. The helper T lymphocyte（Th）1/Th2 ratio after military training was significantly higher than that before military training（P<0.05）. ConclusionsMilitary stress can cause body's immune dysfunction among recruits.

Key words: Humoral immunity, Cellular immunity, Stress, Psychology, Recruit

CLC Number:

R446.62

AN Liyun, WANG Fukun, JIA Keran, LIU Yanli, TANG Fei, WANG Xianling, LI Fang. Influence of military stress on immune function among recruits[J]. Laboratory Medicine, 2016, 31(3): 189-194.

Figures/Tables 7

References 13

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组别	例数	因子									总分
组别	例数	躯体性	强迫症状	人际关系	抑郁	焦虑	敌对	恐怖	偏执	精神病性	总分
军事训练前	60	1.28±0.31	1.51±0.40	1.41±0.46	1.34±0.43	1.65±0.30	1.36±0.39	1.11±0.28	1.31±0.42	1.51±0.41	1.36±0.33
军事训练后	60	1.62±0.66^*	1.62±0.57	1.55±0.61	1.63±0.66^*	1.78±0.49	1.41±0.46	1.21±0.33	1.57±0.61^*	1.64±0.50	1.83±0.62^*

组别	例数	因子									总分
组别	例数	躯体性	强迫症状	人际关系	抑郁	焦虑	敌对	恐怖	偏执	精神病性	总分
军事训练前	60	1.28±0.31	1.51±0.40	1.41±0.46	1.34±0.43	1.65±0.30	1.36±0.39	1.11±0.28	1.31±0.42	1.51±0.41	1.36±0.33
军事训练后	60	1.62±0.66^*	1.62±0.57	1.55±0.61	1.63±0.66^*	1.78±0.49	1.41±0.46	1.21±0.33	1.57±0.61^*	1.64±0.50	1.83±0.62^*

组别	例数	IgG	IgA	IgM	C3	C4
军事训练前	60	12.82±1.76	1.98±0.55	1.96±0.56	1.13±0.22	0.25±0.08
军事训练后	60	11.91±1.70^**	1.78±0.52^**	1.80±0.43^*	1.12±0.28	0.27±0.09

组别	例数	IgG	IgA	IgM	C3	C4
军事训练前	60	12.82±1.76	1.98±0.55	1.96±0.56	1.13±0.22	0.25±0.08
军事训练后	60	11.91±1.70^**	1.78±0.52^**	1.80±0.43^*	1.12±0.28	0.27±0.09

组别	例数	B淋巴细胞	NK细胞
军事训练前	60	11.52±3.36	16.45±4.83
军事训练后	60	10.76±3.22	13.81±4.26^*