›› 2014, Vol. 29 ›› Issue (2): 186-190.DOI: 10.3969/j.issn.1673-8640.2014.02.023

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The application significance and research development of hepatitis B virus-large protein detection

LIU Jintao.   

  1. Department of Clinical Laboratory, the Second Hospital of Hohhot, Inner Mongolia Autonomous Region Hohhot 010031, China
  • Received:2013-01-11 Online:2014-02-20 Published:2014-02-20

Abstract: Currently, the research about hepatitis B virus(HBV)-large surface protein (LP) is still in the infancy phase. The review describes the structure, function, testing technology and application prospects of HBV-LP and indicates the collaborative determination of hepatitis B serum marker (HBV-M), anti-hepatitis B virus core antibody IgM (HBcIgM), HBV DNA with HBV-LP, which can not only improve the detection rate, avoid missed diagnosis, but also offer more reliable judgment reference for the clinical diagnosis of HBV infection, replication, infection judgment and antiviral efficacy index.

Key words: Hepatitis B virus, Large surface protein, Application significance, Development prospect

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