Research progress on determination and treatment of carbapenem-resistant Klebsiella pneumoniae

doi:10.3969/j.issn.1673-8640.2024.06.018

Abstract

Abstract:

With the increasing determination rate of carbapenem-resistant Klebsiella pneumoniae（CRKP），strong CRKP drug resistance，rapid dissemination and high patients' mortality have brought challenges to clinical treatment. At present，the determination methods of CRKP mainly include carbapenem inactivation method（CIM），Carba NP test，mass spectrometry，enzymic immunochromatography and molecular determination technology. Antibiotic therapy，bacteriophage combined with antibiotics，vaccines and monoclonal antibodies are the main methods to treat CRKP.

Key words: Carbapenem resistance, Klebsiella pneumoniae, Determination, Treatment

CLC Number:

R378.99

SUN Miaoli, WU Qiong, WANG Yingzhi, WANG Jianqiang, GAO Feng, TANG Jin. Research progress on determination and treatment of carbapenem-resistant Klebsiella pneumoniae[J]. Laboratory Medicine, 2024, 39(6): 615-620.

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