Abstract:

Objective To investigate the distribution and drug resistance of Gram-positive bacteria in Cangnan County,and to provide a reference for the clinical prevention and control of nosocomial infection. Methods A total of 517 isolates of Gram-positive bacteria from Cangnan County Second People's Hospital,463 isolates of Gram-positive bacteria from Cangnan County Third People's Hospital and 869 isolates of Gram-positive bacteria from Cangnan County People's Hospital were collected from January 2016 to December 2017. Bacterial identification and drug susceptibility test in vitro were performed. Results Among the 1 849 isolates of Gram-positive bacteria,there were 718 isolates of Staphylococcus aureus（38.83%）,431 isolates of Staphylococcus epidermidis（23.31%）,240 isolates of Staphylococcus haemolyticus（12.98%）,60 isolates of Streptococcus pneumoniae（3.24%）,100 isolates of Streptococcus agalactiae（5.41%）,200 isolates of Enterococcus faecalis（10.82% and 100 isolates of Enterococcus faecium（5.41%）. Among the 718 isolates of Staphylococcus aureus,481 isolates（66.99%） were methicillin-resistant Staphylococcus aureus（MRSA）. All isolates of Staphylococcus were sensitive to tigecycline and linezolid. The isolates ofEnterococcus faecalis were sensitive to vancomycin and tigecycline（100.0%）,and they had different degrees of resistance to linezolid（2.0%）. The isolates of Enterococcus faecium had different degrees of resistance to linezolid（1.0%） and tigecycline（1.0%）. The isolates of Streptococcus pneumoniae were sensitive to tigecycline and vancomycin（100.0%）. Conclusions Among the isolates of Gram-positive bacteria in Cangnan County,Staphylococcus aureus is the main one,followed by Staphylococcus epidermidis,and MRSA is as high as 66.99%. Enterococcus has different degrees of drug resistance.

Key words: Gram-positive bacterium, Staphylococcus aureus, Drug resistance, Drug susceptibility test