Clinical application of the quantitative determination of serum procalcitonin in the diagnosis of bacterial infection

doi:10.3969/j.issn.1673-8640.2015.10.003

Abstract

Abstract: Objective

To evaluate the clinical application significance of serum procalcitonin (PCT) quantitative detemination in the diagnosis of different pathogens (bacterium and non-bacterium, Gram-positive coccus and Gram-negative bacillus), different types (systemic infection and local infection such as urinary and respiratory systems), different populations (male, female and different age groups).

Methods

The pathogens were isolated from outpatients and inpatients from January 2014 to December 2014, meanwhile serum PCT was determined quantitatively, and the results were analyzed statistically.

Results

The serum PCT in bacterium infection group was significantly higher than those in fungus and non-bacterium infection groups, and the difference was statistically significant (P<0.05). The serum PCT in systemic infection group was significantly higher than that in local infection group (P<0.05). There was no statistical significance for serum PCT levels among bacterium infection, respiratory system, urinary system and nervous system infection groups (P> 0.05). In bacterium infection group, serum PCT level in Gram-negative bacillus infection group was higher than that in Gram-positive coccus infection group (P<0.05). However, there was no statistical significance between male and female and for different ages(P>0.05).

Conclusions

Serum PCT can be used as an important indicator of bacterium infection, especially systemic infection.

Key words: Procalcitonin, Bacterium, Fungus, Systemic infection, Local infection, Gram-nagative bacillus, Gram-positive coccus, Sex, Age

CLC Number:

R446.5

HUANG Chenjing, XIA Huafeng, WANG Yin.. Clinical application of the quantitative determination of serum procalcitonin in the diagnosis of bacterial infection[J]. Laboratory Medicine, 2015, 30(10): 980-982.

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