Laboratory Medicine ›› 2018, Vol. 33 ›› Issue (4): 305-311.DOI: 10.3969/j.issn.1673-8640.2018.04.007

• Orginal Article • Previous Articles     Next Articles

Difference of 10-year risk of cardiovascular disease among elderly people through different cardiovascular disease risk assessment systems

SHI Meifang1, SHEN Yifeng2, SHEN Junfei2, WANG Beili2, GUO Wei2, LI Gang1, PAN Baishen2   

  1. 1. Department of Clinical Laboratory,Shanghai Baoshan District Youyi Community Health Service Center,Shanghai 201900,China
    2. Department of Clinical Laboratory,Zhongshan Hospital,Fudan University,Shanghai 200032,China
  • Received:2017-09-14 Online:2018-04-30 Published:2018-04-26

Abstract:

Objective To investigate the epidemiological characteristics of cardiovascular disease in Shanghai Baoshan District Youyi Community elderly people,to compare the difference of 10-year risk of cardiovascular disease through different cardiovascular disease risk assessment systems. Methods A total of 1 983 cases of over 60-year old were enrolled from Shanghai Baoshan District Youyi Community. The baseline data were collected,and fasting venous blood samples were collected to determine total cholesterol(TC) and high-density lipoprotein cholesterol(HDL-C). The baseline data from the derivation cohort of each cardiovascular disease risk score [Framingham risk score,ischemic cerebral vascular disease(ICVD) risk assessment model,Reynold's risk score,SCORE risk score(Spain),SCORE risk score(Finland) and QRISK2 risk score] were compared with the baseline data of elderly people from Shanghai Baoshan District Youyi Community. Framingham risk score,Reynold's risk score and SCORE risk scores and Chinese Adult Dyslipidemia Prevention Guideline(2016 revised edition) atherosclerotic cardiovascular disease(ASCVD) risk algorithm were used to calculate the difference of 10-year risk of cardiovascular disease among elderly people in Shanghai Baoshan District Youyi Community. Results Among the 1 983 elderly people,there were 32(1.61%) cases with cerebrovascular diseases and 56(2.82%) cases with heart diseases. There was difference between the baseline of Youyi Community elderly people and the baseline of derivation cohort. The risk rates of Framingham risk score and Reynold's risk score in predicting 10-year risk of cardiovascular disease were 28.73% and 13.95%, respectively. The risk rates of SCORE risk scores for high risk region and low risk region were 7.29% and 4.14%,respectively. According to related guidelines,the risk rates of Framingham,Reynold's and SCORE(high risk region) risk score were stratified,and there were 11.29% cases in the same risk group and other 88.71% cases with difference in the stratification of risk groups. Conclusions The elderly people in Shanghai Baoshan District Youyi Community have high risk of cardiovascular disease. There exists difference among Framingham,Reynold's and SCORE risk scores in predicting 10-year risk of cardiovascular disease.

Key words: Cardiovascular disease, Framingham risk score, Reynold's risk score, SCORE risk score, Community elderly people, 10-Year risk of cardiovascular disease

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