Correlation study of serum ferritin and high-sensitivity C reactive protein in gestational diabetes mellitus

doi:10.3969/j.issn.1673-8640.2015.09.009

Abstract

Abstract: Objective

To investigate the relationship between serum ferritin (SF) and high-sensitivity C reactive protein (hs-CRP) in patients with gestational diabetes mellitus (GDM) and their clinical significance.

Methods

A total of 86 patients with GDM and 120 pregnant women with normal glucose tolerance (NGT) were enrolled as GDM and NGT groups. SF and hs-CRP were determined. The relationship between SF and hs-CRP in the 2 groups was evaluated,

Results

The SF and hs-CRP in GDM group were higher than those in NGT group (P=0.031 and 0.007). Meanwhile, serum SF was positively correlated with hs-CRP (GDM group: r=0.352, P=0.003; NGT group: r=0.285, P=0.001).

Conclusions

The levels of SF and hs-CRP may play important roles in the progress of GDM. SF and hs-CRP can be used as predictive factors for the prevention and treatment of GDM.

Key words: Ferritin, High-sensitivity C reactive protein, Gestational diabetes mellitus

CLC Number:

R446.1

ZHANG Xianghui, ZHAO Yuanming, SUN Zhuoxiang, CHENG Panpan, JIN Chao. Correlation study of serum ferritin and high-sensitivity C reactive protein in gestational diabetes mellitus[J]. Laboratory Medicine, 2015, 30(9): 903-905.

Figures/Tables 3

References 13

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组别	例数	年龄(岁)	孕周(周)	身高(cm)	孕前体重(kg)	孕前BMI(kg/m²)
GDM组	86	29.61±1.21	27.50±1.36	160.62±1.95	57.85±2.92	22.39±1.37^*
NGT组	120	28.86±1.51	27.43±1.12	160.14±2.45	56.20±3.01	21.89±1.37

组别	例数	年龄(岁)	孕周(周)	身高(cm)	孕前体重(kg)	孕前BMI(kg/m²)
GDM组	86	29.61±1.21	27.50±1.36	160.62±1.95	57.85±2.92	22.39±1.37^*
NGT组	120	28.86±1.51	27.43±1.12	160.14±2.45	56.20±3.01	21.89±1.37

组别	例数	SF(ng/mL)	hs-CRP (mg/L)
GDM组	86	150.08±40.25^*	4.30±0.56^*
NGT组	120	112.68±32.07	2.77±0.32

组别	例数	SF(ng/mL)	hs-CRP (mg/L)
GDM组	86	150.08±40.25^*	4.30±0.56^*
NGT组	120	112.68±32.07	2.77±0.32

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