Abstract:

Objective　To investigate the relationship of trace element zinc（Zn）， iron（Fe） and blood routine test with infection and anemia in children in order to determine and perform trace element supplementary reasonably. Methods　A total of 1 289 children aged 1 to 5 years were enrolled. The 287 children with infection were selected as infection group， and 303 children with anemia were selected as anemia group. The 699 healthy children were selected as control group. The peripheral blood levels of trace elements and blood routine test were determined. Results　The level of peripheral blood Zn in infection group [（63.8±5.6）μmol/L] was lower than that in control group [（69.6±6.3）μmol/L] with statistical significance（P＜0.05）. The level of peripheral blood Fe in infection group [（7.74±0.26）mmol/L] had no statistical significance with that in control group（P＞0.05）. The levels of white blood cell（WBC） [（10.9±2.4）×10⁹/L] and 5% neutrophilic granulocyte（NEUT） [（37.9±14.5）%] in infection group were higher than those in control group . The level of peripheral blood Fe in anemia group [（7.68±0.23）mmol/L] was lower than that in control group [（7.80±0.26）mmol/L] with statistical significance（P＜0.01）， and the level of peripheral blood Zn in anemia group [（65.1±6.3）μmol/L] had no statistical significance with that in control group（P＞0.05）. Hemoglobin（Hb） in anemia group[（110.5±6.8）g/L] was lower than that in control group [（127.4±5.6）g/L， P＜0.05]. The contents of red blood cell（RBC）， erythrocyte mean corpuscular volume（MCV）， mean corpuscular hemoglobin（MCH） and mean corpusular hemoglobin concentration（MCHC） in anemia group were lower than those in control group with statistical significance（P＜0.01）. The level of Fe in anemia group was lower than that in infection group with statistical significance（P＜0.05）. Conclusions　The changes of trace elements in peripheral blood of children with infection and anemia are significant， especially Zn and Fe， with the realtionship of blood routine test.

Key words: Zn, Fe, Infection, Anemia, Change