Abstract: Objective To review the laboratory data of one human case infected with babesia, in order to gain experience and improve the diagnosis level. Methods The histograms of red blood cell (RBC), platelet (PLT) and white blood cell(WBC) VCS scatterplot were analyzed. The parasite morphology was observed in peripheral blood and bone marrow smears. DNA extracted from peripheral blood of the patients with plasmodium vivax, voles babesia and babesia DNA-specific primers by polymerase chain reaction(PCR). Results RBC histogram peak reduced, and its width increased. PLT histogram had no abnormality. The non-WBC area of WBC VCS scatter plot had particle group. Peripheral blood and bone marrow smears emerged a large number of quasi plasmodium falciparum parasites. The results of PCR product sequencing showed that the sequencing results had 96% and 99% homology with the 18s ribosomal DNA sequence of voles babesia and babesia. Conclusions The patient is infected with voles babesia.

Key words: Babesia, Plasmodium, Infection, Diagnosis